Protein Alignment CaMKII and Camk4

DIOPT Version :9

• Sequence 1: NP_001162833.1
• Gene: CaMKII / 43828
• FlyBaseID: FBgn0264607
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: XP_006525606.1
• Gene: Camk4 / 12326
• MGIID: 88258
• Length: 497
• Species: Mus musculus
• Alignment Length: 452
• Identity: 161/452 - (35%)
• Similarity: 254/452 - (56%)
• Gaps: 59/452 - (13%)

  Fly    12 DNYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTARDFQKLEREARICRKLHHPNIVRL 76
            |.::::.|||:||.|||.||.||.|...:|.|::  ||..  |.:.:..|..:..:|.||||::|
Mouse    68 DFFEVESELGRGATSIVYRCKQKGTQKPYALKVL--KKTV--DKKIVRTEIGVLLRLSHPNIIKL 128

  Fly    77 HDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQNGVVHRDLKPEN 141
            .:..:......||.:||||||||:.||.:.:|||.||:..::||||:|.:.|:||:|||||||||
Mouse   129 KEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHENGIVHRDLKPEN 193

  Fly   142 LLLASKAKGAAVKLADFGLAIEVQGDHQAWF-GFAGTPGYLSPEVLKKEPYGKSVDIWACGVILY 205
            ||.|:.|..|.:|:|||||:..|  :||... ...|||||.:||:|:...||..||:|:.|:|.|
Mouse   194 LLYATPAPDAPLKIADFGLSKIV--EHQVLMKTVCGTPGYCAPEILRGCAYGPEVDMWSVGIITY 256

  Fly   206 ILLVGYPPFWDE--DQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPNKRITAAEALK 268
            |||.|:.||:||  ||. ::.:|....|.:.||.||.|:..||:|:.:::.::|.||:|..:||:
Mouse   257 ILLCGFEPFYDERGDQF-MFRRILNCEYYFISPWWDEVSLNAKDLVKKLIVLDPKKRLTTFQALQ 320

  Fly   269 HPWICQRERVASVVHRQETVDCLKKFNARRKLKGAILTTMLATRNFSSRSMITKKGEG------- 326
            |||:  ..:.|:.||.......|::||||||||.|:...:.::|..|:.|..|...|.
Mouse   321 HPWV--TGKAANFVHMDTAQKKLQEFNARRKLKAAVKAVVASSRLGSASSSHTSIQENHKASSDP 383

  Fly   327 ---SQVKESTDSSSTTLEDDDIKEDK---KGTVD-------------------RSTTVVSKEPED 366
               ...|:|||.....::::|.:||:   :.:.|                   .::::|.::|||
Mouse   384 PSTQDAKDSTDLLGKKMQEEDQEEDQVEAEASADEMRKLQSEEVEKDAGVKEEETSSMVPQDPED 448

  Fly   367 IRILCPAKTYQQNI-GNSQCSSAARRQEIIKITEQLIEAINSGDFDGYTKICDPHLTAFEPE 427
                 ..:|....: .:|:....:..:|:..:||:  ||.::|       :..|...|.:||
Mouse   449 -----ELETDDPEMKRDSEEKLKSVEEEMDPMTEE--EAPDAG-------LGVPQQDAIQPE 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CaMKII	NP_001162833.1	STKc_CaMKII	12..303	CDD:270988	131/293 (45%)
		S_TKc	14..272	CDD:214567	117/260 (45%)
		CaMKII_AD	390..517	CDD:285524	10/38 (26%)
Camk4	XP_006525606.1	STKc_CaMKIV	66..359	CDD:270987	132/299 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X46
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920