Protein Alignment CaMKII and Camk2g

DIOPT Version :9

• Sequence 1: NP_001162833.1
• Gene: CaMKII / 43828
• FlyBaseID: FBgn0264607
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: XP_006518551.1
• Gene: Camk2g / 12325
• MGIID: 88259
• Length: 588
• Species: Mus musculus
• Alignment Length: 586
• Identity: 388/586 - (66%)
• Similarity: 442/586 - (75%)
• Gaps: 74/586 - (12%)

  Fly     1 MAAPAACTRFSDNYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTARDFQKLEREARIC 65
            ||..|.||||:|:|.:.|||||||||:|:|||:|::..|:||||||||||:|||.||||||||||
Mouse     1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARIC 65

  Fly    66 RKLHHPNIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQN 130
            |.|.|||||||||||.||.:|||||||||||||||||||||:||||||||||.||||||||.||:
Mouse    66 RLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQH 130

  Fly   131 GVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDHQAWFGFAGTPGYLSPEVLKKEPYGKSV 195
            .:|||||||||||||||.||||||||||||||||||:.||||||||||||||||||:|:||||.|
Mouse   131 DIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPV 195

  Fly   196 DIWACGVILYILLVGYPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPNKR 260
            |||||||||||||||||||||||||:||.||||||||:|||||||||||||||||||||:||.||
Mouse   196 DIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKR 260

  Fly   261 ITAAEALKHPWICQRERVASVVHRQETVDCLKKFNARRKLKGAILTTMLATRNFS---------- 315
            |||.:||||||:|||..|||::||||||:||:|||||||||||||||||.:||||
Mouse   261 ITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAILTTMLVSRNFSVGRQSSAPAS 325

  Fly   316 ------------SRSMITKKGEG------------------------------------------ 326
                        ::|::.||.:|
Mouse   326 PAASAAGLAGQAAKSLLNKKSDGGVKKRKSSSSVHLMPQSNNKNSLVSPAQEPAPLQTAMEPQTT 390

  Fly   327 ------SQVKESTDSSSTTLEDDDIKEDKKGTVDRSTTVVSKEPEDIRILCPAKTYQQNIGNSQC 385
                  ..:|.||:|.:||.||:|:|.....|.:.|.....:.|.|  ...|:...|..  .|.|
Mouse   391 VVHNATDGIKGSTESCNTTTEDEDLKAAPLRTGNGSLVPEGRSPRD--RTAPSAGMQPQ--PSLC 451

  Fly   386 SSAARRQEIIKITEQLIEAINSGDFDGYTKICDPHLTAFEPEALGNLVEGIDFHKFYFENVLGKN 450
            |||.|:|||||||||||||||:|||:.|||||||.||:||||||||||||:|||||||||:|.||
Mouse   452 SSAMRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKN 516

  Fly   451 CKAINTTILNPHVHLLGEEAACIAYVRLTQYIDKQGHAHTHQSEETRVWHKRDNKWQNVHFHRSA 515
            .|.|:|||||||||::||:||||||:|||||||.||...|.|||||||||:||.||.|||:|.|.
Mouse   517 SKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWLNVHYHCSG 581

  Fly   516 S 516
            :
Mouse   582 A 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CaMKII	NP_001162833.1	STKc_CaMKII	12..303	CDD:270988	245/290 (84%)
		S_TKc	14..272	CDD:214567	220/257 (86%)
		CaMKII_AD	390..517	CDD:285524	99/127 (78%)
Camk2g	XP_006518551.1	STKc_CaMKII	12..303	CDD:270988	245/290 (84%)
		CaMKII_AD	456..583	CDD:285524	99/127 (78%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	476	1.000	Domainoid score	I429
eggNOG	1	0.900	-	-		E1_KOG0033
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	789	1.000	Inparanoid score	I513
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52374
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	1	1.000	-	-		FOG0000706
OrthoInspector	1	1.000	-	-		otm44116
orthoMCL	1	0.900	-	-		OOG6_100515
Panther	1	1.100	-	-	LDO	PTHR24347
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X46
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.840