DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CaMKII and camk1d

DIOPT Version :9

Sequence 1:	NP_001162833.1	Gene:	CaMKII / 43828	FlyBaseID:	FBgn0264607	Length:	531	Species:	Drosophila melanogaster
Sequence 2:	XP_002935295.2	Gene:	camk1d / 100493115	XenbaseID:	XB-GENE-5874342	Length:	395	Species:	Xenopus tropicalis

Alignment Length:	375	Identity:	140/375 - (37%)
Similarity:	207/375 - (55%)	Gaps:	26/375 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 YDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTARDFQKLEREARICRKLHHPNIVRLHD 78
            :..||.||.||||.|....:|:||..||.|.|..|.|..:: ..:|.|..:.||:.|.|||.|.|
Frog    24 FQFKEVLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKE-SSIENEIAVLRKIKHENIVALED 87

  Fly    79 SIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQNGVVHRDLKPENLL 143
            ..:..::.|||..||:|||||:.||.:.||:|.|||..|:|:|::|::.|:.|:|||||||||||
Frog    88 IYESPSHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVSYLHRLGIVHRDLKPENLL 152

  Fly   144 LASKAKGAAVKLADFGLAIEVQGDHQAWFGFAGTPGYLSPEVLKKEPYGKSVDIWACGVILYILL 208
            ..|:.:.:.:.::||||: :::|.........|||||::||||.::||.|:||.|:.|||.||||
Frog   153 YFSQVEESKIMISDFGLS-KMEGKGDVMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILL 216

  Fly   209 VGYPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPNKRITAAEALKHPWIC 273
            .|||||:||:..:|:.||....|::.||.||.::..||:.|..::..:.|||.|..:||:||||.
Frog   217 CGYPPFYDENDSKLFEQILKADYEFDSPYWDDISESAKDFIQHLMEKDSNKRYTCEQALRHPWIA 281

  Fly   274 QRERVASVVHRQETVDCLKKFNARRKLKGAILTTMLATRNFSSRSMITKKGEGSQVKESTDSSST 338
            ....:...:|...:....|.| |:.|.:.|...|.:...   .|.:.....:.|......:|.::
Frog   282 GDTALCKNIHESVSAQIRKNF-AKSKWRQAFNATAVVRH---MRKLHLGSSQDSSSVSGGNSPAS 342

  Fly   339 TLEDDDIKEDKKGTVDRSTTVVSKEPEDIRILCPAKTYQQNIGNSQCSSA 388
            .|.|...::|.|.                    |:..|....|.|..|||
Frog   343 PLPDGTSRKDCKS--------------------PSNPYGFLSGVSSSSSA 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CaMKII	NP_001162833.1	STKc_CaMKII	12..303	CDD:270988	124/288 (43%)
		S_TKc	14..272	CDD:214567	117/257 (46%)
		CaMKII_AD	390..517	CDD:285524
camk1d	XP_002935295.2	PKc_like	13..313	CDD:389743	125/291 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010