DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CaMKII and XB22062963

DIOPT Version :9

Sequence 1:	NP_001162833.1	Gene:	CaMKII / 43828	FlyBaseID:	FBgn0264607	Length:	531	Species:	Drosophila melanogaster
Sequence 2:	NP_001135626.1	Gene:	XB22062963 / 100216185	XenbaseID:	XB-GENE-22062964	Length:	385	Species:	Xenopus tropicalis

Alignment Length:	383	Identity:	121/383 - (31%)
Similarity:	210/383 - (54%)	Gaps:	43/383 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 SDNYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTARDFQKLEREAR----ICRKLHHP 71
            :|.|||.|.|....|..:  |:.:....:   ::...||...:|.:|:.|.|:    |.:.::||
Frog    21 TDKYDIGELLCAKEFCEI--CLAREIPTD---RLFLCKKFLKKDGRKVRRAAKNEISILKLVNHP 80

  Fly    72 NIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQNGVVHRD 136
            ||::|.|:.:.:...|::.:|.|||::|:.|.|:.:|||.|||:.::|:||:|::.|...:|||:
Frog    81 NILQLIDTFETKKEFYIIQELATGGDVFDWISAQGYYSERDASNVLRQLLEAVSYLHSLRIVHRN 145

  Fly   137 LKPENLLLASKAKGAAVKLADFGLAIEVQGDHQAWFGFAGTPGYLSPEVLKKEPYGKSVDIWACG 201
            ||.|||:..::...:.|.|.||.|:....|:...   ..|||.||:|||:.:..||:.||.||.|
Frog   146 LKLENLMYYNQNNHSKVVLRDFYLSCFESGEITE---PCGTPEYLAPEVVSRHRYGRPVDCWAVG 207

  Fly   202 VILYILLVGYPPFWDEDQ--------HRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPN 258
            |:::|||.|.|||:||::        .:::.:|.||.|::.||.||.::..||:|:::::.::..
Frog   208 VVMFILLSGNPPFYDENEEENSESHNRKIFRKILAGEYEFDSPYWDVISASAKDLVSRLMEMDQE 272

  Fly   259 KRITAAEALKHPWICQRERVASVVHRQETVDC--LKKFNARRKLKGAILTTMLATRNFSSRSMIT 321
            :||||.:||.|.||  ....||..:.:|.| |  ::|..|:.|.:.||..|....|        .
Frog   273 QRITAQDALAHTWI--SGNAASERNLKEGV-CAQIEKNFAKAKWRKAIRVTTFMQR--------L 326

  Fly   322 KKGEGSQVKESTDSSSTTLEDDDIKEDKKGTVDRSTTVVSKEP-------EDIRILCP 372
            :..||:::..:..||.:...:..:   ...:..|.....::||       |.::..||
Frog   327 RAPEGARLPVTPRSSMSVSHEVTV---APASPSRHPPHCTEEPACGSDPTESLKAPCP 381

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CaMKII	NP_001162833.1	STKc_CaMKII	12..303	CDD:270988	107/304 (35%)
		S_TKc	14..272	CDD:214567	96/269 (36%)
		CaMKII_AD	390..517	CDD:285524
XB22062963	NP_001135626.1	PKc_like	22..286	CDD:304357	97/271 (36%)
XB22062963	NP_001135626.1	S_TKc	24..286	CDD:214567	96/269 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010