Protein Alignment CaMKII and caskb

DIOPT Version :10

• Sequence 1: NP_001162833.1
• Gene: CaMKII / 43828
• FlyBaseID: FBgn0264607
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: XP_073808534.1
• Gene: caskb / 100148073
• ZFINID: ZDB-GENE-030131-4473
• Length: 948
• Species: Danio rerio
• Alignment Length: 589
• Identity: 192/589 - (32%)
• Similarity: 293/589 - (49%)
• Gaps: 96/589 - (16%)

  Fly    10 FSDNYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTAR---DFQKLEREARICRKLHHP 71
            |.|.|::.|.:|||.||:|:||:.:.||.:||.||::....|:.   ..:.|:|||.||..|.||
Zfish     8 FEDVYELCEVIGKGPFSVVRRCINRDTGQQFAVKIVDVASFTSSPGLSTEDLKREASICHMLKHP 72

  Fly    72 NIVRLHDSIQEENYHYLVFDLVTGGELFEDIVARE----FYSEADASHCIQQILESVNHCHQNGV 132
            :||.|.::...:...|:||:.:.|.:|..:||.|.    .||||.|||.::||||::.:||.|.|
Zfish    73 HIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEALRYCHDNNV 137

  Fly   133 VHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDHQAWFGFAGTPGYLSPEVLKKEPYGKSVDI 197
            :|||:||..:|||||...|.|||..||:||::........|..|||.:::|||:|:|||||.||:
Zfish   138 IHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMAPEVVKREPYGKPVDV 202

  Fly   198 WACGVILYILLVGYPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPNKRIT 262
            |.|||||:|||.|..||:. .:.||:..|..|.|.....:|..::..||:|:.:||.::|.:|||
Zfish   203 WGCGVILFILLSGCLPFYG-TKERLFEAIIKGKYKMNPRQWAHISESAKDLVRRMLMLDPAERIT 266

  Fly   263 AAEALKHPWICQRERVASVVHRQETVDCLKKFNARRKLKGAILTTMLATR-------------NF 314
            ..|||.|||:.:|:|.:..:|..|||:.|:|||||||||||:|..:.:.:             :|
Zfish   267 VYEALNHPWLKERDRYSYKIHLPETVEQLRKFNARRKLKGAVLAAVSSHKFNSFYGDPPEDLHDF 331

  Fly   315 S----SRSMITKKGEGSQVKES-------TDSSSTTL-------EDDDIKE-----DKKGTVDRS 356
            |    |..::..:...|||.:|       ||.|...|       :|..:..     ||..|  ||
Zfish   332 SEDPTSSGLLAAERAVSQVLDSLEEIHALTDCSEKDLDFLHSVFQDQHLHTLLDLYDKINT--RS 394

  Fly   357 TTVVSKEPEDI-----RILCPAKTYQQNIGNSQCSSAARRQEIIKITEQ--LIEAINSGDFDGYT 414
            :..:...|.|.     .:|.....|.:|:         ..:|:.:|..|  .:..:.:.|...:.
Zfish   395 SPQIRNPPSDAVQRAKEVLETISCYPENM---------EAKELKRILTQPHFMALLQTHDVVAHE 450

  Fly   415 KICD-----------PHLTAFEPEAL-GNL-------VEGIDFHKFYFENVLGKNCKAINTTILN 460
            ...|           |:|....||:: |:|       |..:.|.| ..:..:|...|      :|
Zfish   451 VYSDDALRVTPPPTSPYLNGDSPESVNGDLDLENVTRVRLVQFQK-NTDEPMGITLK------MN 508

  Fly   461 PHVHLLGEEAACIAYVRLTQYIDKQGHAHTHQSEETRVWHKRDNKWQNVHFHRSASAKISGATTF 525
            ...|.:      :|.:.....|.:||..|.  .:|.|..:......|.|...:....::.|:.||
Zfish   509 DLNHCI------VARIMHGGMIHRQGTLHV--GDEIREINGISVANQTVEQLQKMLREMRGSITF 565

  Fly   526 DFIP 529
            ..:|
Zfish   566 KIVP 569

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CaMKII	NP_001162833.1	STKc_CaMKII	12..303	CDD:270988	135/297 (45%)
		CaMKII_AD	390..517	CDD:285524	27/147 (18%)
caskb	XP_073808534.1	None