Protein Alignment CaMKII and chek2

DIOPT Version :10

• Sequence 1: NP_001162833.1
• Gene: CaMKII / 43828
• FlyBaseID: FBgn0264607
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: XP_031750712.1
• Gene: chek2 / 100144952
• XenbaseID: XB-GENE-5765421
• Length: 516
• Species: Xenopus tropicalis
• Alignment Length: 350
• Identity: 119/350 - (34%)
• Similarity: 183/350 - (52%)
• Gaps: 29/350 - (8%)

  Fly    10 FSDNYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTARDFQ-----KLEREARICRKLH 69
            |||.|.:...:|.||...||...|||...:.|.|||:.:|.......     .::.|..|.:|:.
 Frog   187 FSDKYIMSRPIGSGACGEVKLAFQKSACKKVAVKIISKRKFKMSTSSNEHPISVDTEIEILKKID 251

  Fly    70 HPNIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQNGVVH 134
            ||.|:::.:....|::.|:|.:|:.|||||:.:|:.....|:.|.....|:|.:|.:.|:|||:|
 Frog   252 HPCIIKIENFFDSEDFFYIVLELMEGGELFDKVVSSTRLRESTAKLYFYQMLLAVQYLHENGVIH 316

  Fly   135 RDLKPENLLLASKAKGAAVKLADFGLAIEVQGDHQAWFGFAGTPGYLSPEVLK---KEPYGKSVD 196
            |||||||:||:|..:...:|:.|||.: ::.|:........|||.||:||||.   ...|.::||
 Frog   317 RDLKPENVLLSSSNEECCIKITDFGQS-KILGETSLMRTLCGTPTYLAPEVLNTAGTTGYSRAVD 380

  Fly   197 IWACGVILYILLVGYPPFWDEDQH-RLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPNKR 260
            .|:.||||::.|.|||||.:::.. .|.:||..|.|.|....||.|:.:|.:|:.::|.|:|.:|
 Frog   381 YWSLGVILFVCLSGYPPFSEQNSKIPLKNQIAEGKYTYIPAAWDAVSEQALDLVKKLLVVDPEQR 445

  Fly   261 ITAAEALKHPWICQRERVASVVHRQETVDCLKKFNARRKLKGAILTTMLATRNFSSRSMITKKGE 325
            :|..:||:|||:               .|...|..|.|.:.|...|....::..:||    |:|.
 Frog   446 LTTKQALEHPWL---------------QDDDMKHTAERLMYGVDHTMPPPSKINTSR----KRGH 491

  Fly   326 GSQVKESTDSSSTTLEDDDIKEDKK 350
            ......||.:.|..|.....|..||
 Frog   492 EWDQDASTSAFSEILPTTAEKRAKK 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CaMKII	NP_001162833.1	STKc_CaMKII	12..303	CDD:270988	104/299 (35%)
		CaMKII_AD	390..517	CDD:285524
chek2	XP_031750712.1	FHA_CHK2	64..175	CDD:438718
		STKc_Chk2	184..457	CDD:270986	101/270 (37%)