DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CaMKII and pnck

DIOPT Version :9

Sequence 1:	NP_001162833.1	Gene:	CaMKII / 43828	FlyBaseID:	FBgn0264607	Length:	531	Species:	Drosophila melanogaster
Sequence 2:	NP_001096459.1	Gene:	pnck / 100125076	XenbaseID:	XB-GENE-961042	Length:	339	Species:	Xenopus tropicalis

Alignment Length:	334	Identity:	134/334 - (40%)
Similarity:	198/334 - (59%)	Gaps:	17/334 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 YDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTARDFQKLEREARICRKLHHPNIVRLHD 78
            |:|||:||.||||.|....:|::....|.|.|..|.|..:: ..:|.|..:.:|:.|.|||.|.|
Frog    18 YNIKEKLGAGAFSEVVLAQEKNSERLVALKCIPKKALRGKE-AVVENEIAVLKKITHKNIVSLED 81

  Fly    79 SIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQNGVVHRDLKPENLL 143
            ..:...:.||..:||||||||:.|:.|.:|:|.|||..|:|:|::|.:.|..|:|||||||||||
Frog    82 IYESPTHLYLAMELVTGGELFDRIIERGYYTEKDASQLIRQVLDAVQYLHNMGIVHRDLKPENLL 146

  Fly   144 LASKAKGAAVKLADFGLAIEVQGDHQAWFGFAGTPGYLSPEVLKKEPYGKSVDIWACGVILYILL 208
            .|:..:.:.:.::||||:....|...|  ...|||||::||:|:::||||:||:||.|||.||||
Frog   147 YATPFEDSKIMISDFGLSKIEDGGMMA--TACGTPGYVAPELLEQKPYGKAVDVWAIGVISYILL 209

  Fly   209 VGYPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPNKRITAAEALKHPWIC 273
            .|||||:||:...|::||....|::.||.||.::..||:.|..:|...|.||:|..:||:|||||
Frog   210 CGYPPFYDENDSELFNQILKAEYEFDSPYWDDISESAKDFIRHLLEREPEKRLTCEQALQHPWIC 274

  Fly   274 QRERVASVVHRQETVDCLKKFNARRKLKGAILTTMLATRNFSSRSM---ITKKGEGSQVKESTDS 335
            ....:...:|...:....|.| ||.:.|          |.|::.|.   |||.|:.:..:...:.
Frog   275 GDTALERDIHGSVSEQIQKNF-ARTQWK----------RAFNATSFLRHITKMGQSADTEAVENH 328

  Fly   336 SSTTLEDDD 344
            .....::.|
Frog   329 GEAAPQEKD 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CaMKII	NP_001162833.1	STKc_CaMKII	12..303	CDD:270988	126/288 (44%)
		S_TKc	14..272	CDD:214567	117/257 (46%)
		CaMKII_AD	390..517	CDD:285524
pnck	NP_001096459.1	STKc_CaMKI_beta	14..290	CDD:271071	121/274 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X46
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010