Protein Alignment CaMKII and camk2a

DIOPT Version :10

• Sequence 1: NP_001162833.1
• Gene: CaMKII / 43828
• FlyBaseID: FBgn0264607
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: XP_012813848.1
• Gene: camk2a / 100101771
• XenbaseID: XB-GENE-868353
• Length: 516
• Species: Xenopus tropicalis
• Alignment Length: 527
• Identity: 374/527 - (70%)
• Similarity: 435/527 - (82%)
• Gaps: 25/527 - (4%)

  Fly     3 APAACTRFSDNYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTARDFQKLEREARICRK 67
            |...|||||:.|.:.|||||||||||:|||:..:|.|:||||||||||:|||.|||||||||||.
 Frog     2 ATITCTRFSEEYQLFEELGKGAFSIVRRCVKVLSGQEYAAKIINTKKLSARDHQKLEREARICRL 66

  Fly    68 LHHPNIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQNGV 132
            |.|||||||||||.||.:|||||||||||||||||||||:|||||||||||||||:|.||||.||
 Frog    67 LKHPNIVRLHDSISEEGHHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGV 131

  Fly   133 VHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDHQAWFGFAGTPGYLSPEVLKKEPYGKSVDI 197
            |||||||||||||||.||||||||||||||||:|:.||||||||||||||||||:|:||||:||:
 Frog   132 VHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGKAVDL 196

  Fly   198 WACGVILYILLVGYPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPNKRIT 262
            ||||||||||||||||||||||||||.||||||||:|||||||||||||:|||:|||:||:||||
 Frog   197 WACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRIT 261

  Fly   263 AAEALKHPWICQRERVASVVHRQETVDCLKKFNARRKLKGAILTTMLATRNFS-SRSMITKKGEG 326
            ||||||||||..|..|||.:||||||||||||||||||||||||||||||||| .:|...||.:|
 Frog   262 AAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSGGKSGSNKKNDG 326

  Fly   327 ---------SQVKESTDSSSTTLEDDDIKEDKKGTVDRSTTVVSKEPEDIRILCPAKTYQQNIGN 382
                     .|:.||::|::||:||:|.|:......:.:.|...:.|     :.|.|.
 Frog   327 VKKRKSSSSVQLMESSESTNTTIEDEDTKDFSLAAQNENITPGLENP-----IAPKKP------- 379

  Fly   383 SQCSSAARRQEIIKITEQLIEAINSGDFDGYTKICDPHLTAFEPEALGNLVEGIDFHKFYFENVL 447
               |...|:|||||:||||||||::|||:.|||:|||.:||||||||||||||:|||:|||||:.
 Frog   380 ---SQTVRKQEIIKVTEQLIEAISNGDFECYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLW 441

  Fly   448 GKNCKAINTTILNPHVHLLGEEAACIAYVRLTQYIDKQGHAHTHQSEETRVWHKRDNKWQNVHFH 512
            .::.|.::|||||||:||:|:|:|||||:|:|||:|..|...|.|||||.:||:||.||||||||
 Frog   442 SRSNKPLHTTILNPHIHLMGDESACIAYIRITQYLDTSGVPRTAQSEETCIWHRRDGKWQNVHFH 506

  Fly   513 RSASAKI 519
            ||.:..:
 Frog   507 RSGAPSV 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CaMKII	NP_001162833.1	STKc_CaMKII	12..303	CDD:270988	247/290 (85%)
		CaMKII_AD	390..517	CDD:285524	88/126 (70%)
camk2a	XP_012813848.1	STKc_CaMKII	11..302	CDD:270988	247/290 (85%)
		CaMKII_AD	384..511	CDD:285524	88/126 (70%)