Protein Alignment apolpp and vtg5

DIOPT Version :9

• Sequence 1: NP_001259085.1
• Gene: apolpp / 43827
• FlyBaseID: FBgn0087002
• Length: 3351
• Species: Drosophila melanogaster
• Sequence 2: NP_001020360.2
• Gene: vtg5 / 64260
• ZFINID: ZDB-GENE-001201-4
• Length: 1358
• Species: Danio rerio
• Alignment Length: 1624
• Identity: 326/1624 - (20%)
• Similarity: 575/1624 - (35%)
• Gaps: 459/1624 - (28%)

  Fly    19 LTIAVNAENACNLGCPKSDNGLLKYIPGNYYDYSFDSILTIGASSDVPNDS-DDTSLKVSGSAKI 82
            ||:|:.|....||        :.::.....|.|.::::|..|    :|.:. ....:|||....:
Zfish     8 LTVALVASQQMNL--------VPEFAHDKTYVYKYEALLLGG----LPQEGLARAGIKVSSKVHL 60

  Fly    83 FAKGNCGYTLQL------------------SSVKVTNTKESVEKKILNSIQKPVQFTLVSGILEP 129
            .|.....|.::|                  .:.|:|:.       :...:|.|::|...:|:: .
Zfish    61 SAMTENTYLMKLMDPLLYEYAGTWPRDPFVPATKLTSA-------LAAQLQIPIKFEYANGVV-G 117

  Fly   130 QICSDSSDLDYSLNIKRAVVSLLQ------SGIEAEHEVDVFGMCPTHTSTSKVGNAN--IITKA 186
            ::.:.:......:|:.|.::::||      ..|....|....|:|.||...::....|  |:||:
Zfish   118 KVFAPAGVSPTVMNLYRGILNILQLNLKKTQNIYEMQEAGAQGVCRTHYVINEDPKTNHIIVTKS 182

  Fly   187 RNLNSCSHREQINSGLV-SGKVNEKAGITSSLLLQA--NYIKESRIVNHLIENVQLTETYKF--I 246
            ::|:.|..|...:.||. :.:..|......||:..|  |||.:......||....:.|.|:|  .
Zfish   183 KDLSHCQERIMKDVGLAYTERCAECTKRVKSLIETATYNYIMKPADNGALIAEATVEEVYQFSPF 247

  Fly   247 GNTKRNSDISAK-VVTILKL-KNP-SGTKANSPGTGS---TVRSLIFQRP-ETYTSKNINALKT- 303
            ......:.:.|| .:..::: |.| ...||:....||   ...|.|.|.| :....|:..|...
Zfish   248 NEIHGAAMMEAKQTLAFVEIEKTPVVPIKADYMPRGSLQYEFASEILQTPLQLMKIKDAPAQTVE 312

  Fly   304 ILSDLVDSTGDYVKKETAKKFVEFIRLLRQSDSETLLELAAFPHPNKVLARKVYLDGLFRTSTAE 368
            :|..||.:..|.|..:...|||:.::|||.:..|. :|.......:|.:.|:..||.|    .|.
Zfish   313 VLKHLVANNKDMVHDDAPFKFVQLVQLLRVATLEK-IEAIWSQFKDKPVYRRWLLDAL----PAV 372

  Fly   369 SARVILKQLSKFDEKEKLLA------------ILSLNIVKSVDKETLNQAAS-------QLLPNA 414
            ...||:|.:     |||.||            :::|.:| :.|.||:...||       ..:|..
Zfish   373 GTPVIIKFI-----KEKFLAGEFTTPEFIQTLVIALQMV-TADIETIQMTASLATHEKFASIPAL 431

  Fly   415 PKELYIAVGNLVAKYCLK-NYCQGPEIDAISKKFSDGLKHCKPNTKREEERIVYILKGLGNA--- 475
            .:.:.:..|:|:||:|.. ..|....:..|.:..::.:      :|.:...|...||.:|||
Zfish   432 REVVMLGYGSLIAKHCTAVPTCPAELLRPIHEIATEAI------SKNDIPEITLALKVMGNAGHP 490

  Fly   476 -------KSLSGNTVAALSECASTGRSNRIRVAALHAFSKVKCEE--TLQSKSLELLKNRNEDSE 531
                   |.|.|...||      .....:::|.|:.|...:..:|  .:|..:|:|:.:|....|
Zfish   491 SSLKPIMKLLPGLRTAA------NALPVKVQVDAILALRNIAKKEPKLVQPVALQLVLDRALHPE 549

  Fly   532 LRIEAYLSAISC-PNAEVANQISEIVNSETVNQVGGFISSNLKAIR-----DSTDVSRDQQKYHL 590
            :|:.|.:..... |:..:.:.::..:.:|....|..|..|::|::.     |...|:      ..
Zfish   550 VRMVACIVLFEAEPSVALISSLAGALRTEPNMHVSSFAYSHIKSLTRITAPDMASVA------GA 608

  Fly   591 ANIRV----TKTFPVDYRRYSFNNEVSYKLESLGVGASTDYQIIYSQHGFLPRSSRINVTTEFFG 651
            ||:.:    .|...::| |||....:.|....|.:||:....:|......|||:..........|
Zfish   609 ANVAIKLMNCKLDRLNY-RYSRAFHMDYYYTPLMIGAAGSAYMINDAATILPRAVVAKARAYLAG 672

  Fly   652 TNYNVFEASVRQENVEDVLEYYLGPKGLVNKDFDEIVKLIEVGNNGVAAGGRARRSIVDDVSKIS 716
            ...:|.|..||...:.:.|                             ....|....||.::||.
Zfish   673 AAADVIEFGVRTGGINEAL-----------------------------LKSPAAEESVDRITKIK 708

  Fly   717 KKYKMYGVKNVQDLNLDVSL-----KLFGSELAFLSLGDNIPSSLDDIINYFSTSFEKA--KQEL 774
            :..|  .:.|.:.|..|..|     |:||.|:|:::...:|   :::.|...:....:|  |:.|
Zfish   709 RTLK--ALTNWKALPTDRPLASAYFKVFGQEVAYVNFDKSI---IEEAIPMVTGPKPRALLKEAL 768

  Fly   775 SSFEK----QFSSHHLFLDTDLAYPTSIGVPLELVAQGFAATKVDLAVSLDINAILEQNWQKAKY 835
            .:.::    |::...|..:....:||::|||:|......|.....:.|...|...|.:..:...|
Zfish   769 KALQEGIAFQYAKPLLAAEVRRIFPTAVGVPMEFSWYTAAVAAASVNVQATITPALPEKLESMTY 833

  Fly   836 -RLKFV---------PSVDINANVQIGFN-----AQVLSTG-LRVVSSAHSATGSDITVAVISDG 884
             :||..         |||.:.....:|.|     |.|::.| :|.::....|..:||
Zfish   834 EQLKKTDVQFQAEARPSVALQTFAVMGVNTAFIQAAVMARGKIRTIAPGKVAARADI-------- 890

  Fly   885 EGFNVDLELPREKLELINFNVDTELYVAEQDKQKAIALKGNKKNKNSQPSEICFNQLELVGLNIC 949
                                                 ||||.| ..:.|.|:        ..:|.
Zfish   891 -------------------------------------LKGNYK-VEALPVEL--------PEHIA 909

  Fly   950 IKSSTSLSEVQAGNGNVAERGLSVSEKFHLSRPFNFAVYLTTERKFTFKGIHTQEAFSQKWKLDY 1014
            ..|..:|:.|:....:.|||          |.||                  ..|...|..:..|
Zfish   910 SASFETLAVVRNIEDHSAER----------SVPF------------------VPELSLQNSQASY 946

  Fly  1015 STP-GSKVSHDTTVVYELGNKPKTFSRLSFDNSQCHFAVEGGINNDKNELVVYGQYEQDKEIKKS 1078
            :.. .|:||.|.:|     ..|     ..||.:.|:             .|.|.:.:...|:...
Zfish   947 AGDLSSEVSPDASV-----RAP-----APFDRTLCY-------------AVPYIEIKGCVEVHSH 988

  Fly  1079 KIGFSKNGNEYKPLIEIQDNNGISNSINGYHADGKIVVKKNSNNIERYNFENFQVSNSNNAHVAV 1143
            ...|.:|...:              :|.|:|.....:.:.....:||..||
Zfish   989 NAAFIRNSTLF--------------NIIGHHTARAAISRAEGPAVERLEFE-------------- 1025

  Fly  1144 NGWSDVGTNS---LTSELRISLDH----QTFLIKENLKLENGLYEAGFFINDEHSPENIYGSSIH 1201
               ..||..:   |..::.|..|.    |.||:|....|:.   ||.   |...|.|:...|...
Zfish  1026 ---VQVGPRAAERLVKQINIIDDDTPEGQAFLLKLREILDT---EAK---NTPVSSESSSSSRNS 1081

  Fly  1202 LTIADQSYALKTNGKAAAWSIGSDGSFNFQKLA-------------------------DSNSARA 1241
            .:.:..|.:..|:..:::.|..|..|.:..:::                         |::|..|
Zfish  1082 RSSSSSSSSTSTSSSSSSSSSSSSSSLSSSRMSKTATIIEPFRKFHKDRYLAHHSATKDTSSGSA 1146

  Fly  1242 GSLVENVEIQYKNKQVG---------------------GIKIMSNFDVNKMDVDVEISREQKIGS 1285
            .:..|  ::|.||:.:|                     |.::.:.|       |...:|.|.|.|
Zfish  1147 AASFE--QMQKKNRFLGNDIPPVFAIIARAVRADQKLLGYQLAAYF-------DKPTARVQLIAS 1202

  Fly  1286 IIVKYESNQRHAQDYSLEASAKINKHSIDVISKCDFNGNVYVVDNSLVTSWGT-----LLSAKGE 1345
            .|.: ..|.:...|     .|.::||.:        .|..         |||.     .:.||.|
Zfish  1203 SIAE-NDNMKICAD-----GALLSKHKV--------TGKF---------SWGAECKQYAVFAKAE 1244

  Fly  1346 IG--QRYSAQDININIQGNVQISGKDKVTQW--ILKVIGTPDKT----------NSDFRISRDTS 1396
            .|  ..|.|..:.:               :|  :.|::.|..|.          |:.||..:.|:
Zfish  1245 AGVLGEYPAARLEV---------------EWERLPKIVTTYAKKVCKHILNAAYNTGFRFEKATN 1294

  Fly  1397 --ELIKLTSESQHPQDKISF-AKLNLIVKNQLTAKGEFRVAKNGKGDFTASIDTLKTEPKHKLE 1457
              :.|:||: :...|..::| |::..|..::........|..|..|.|:.:.|.|....||.:|
Zfish  1295 SEKEIELTA-ALPSQKSLNFIARIPEITMSKRDIHLPITVPINPDGTFSINEDFLSWIHKHIME 1357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
apolpp	NP_001259085.1	Vitellogenin_N	43..573	CDD:279663	132/602 (22%)
		DUF1943	605..911	CDD:286281	64/332 (19%)
		DUF1081	932..1031	CDD:283982	20/99 (20%)
		VWD	2789..2931	CDD:214566
vtg5	NP_001020360.2	Vitellogenin_N	24..592	CDD:279663	132/602 (22%)
		DUF1943	626..917	CDD:286281	73/378 (19%)
		DUF1944	1166..1330	CDD:286284	38/209 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4338
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23345
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910