Protein Alignment Actbeta and BMP15

DIOPT Version :9

• Sequence 1: NP_651942.2
• Gene: Actbeta / 43826
• FlyBaseID: FBgn0024913
• Length: 946
• Species: Drosophila melanogaster
• Sequence 2: NP_005439.2
• Gene: BMP15 / 9210
• HGNCID: 1068
• Length: 392
• Species: Homo sapiens
• Alignment Length: 389
• Identity: 89/389 - (22%)
• Similarity: 136/389 - (34%)
• Gaps: 145/389 - (37%)

  Fly   651 GTQYRQYRILEFSAQNRRVPSQKLSIRSAQIH-------------IRIDKPHSLWIEKAKSLPEK 702
            |.|.|:.|:|..|.:.    ..:|..|||..|             :|:.||
Human    54 GEQPRKPRLLGHSLRY----MLELYRRSADSHGHPRENRTIGATMVRLVKP-------------- 100

  Fly   703 HLLNTKRKWGANKPHH---RIKIWVFQLSTSINITEKGIDKAIIFRASFQVDPKNL--------- 755
             |.|..|      ||.   .|:|..|.|..:..:.:. :...:::|...|:...||
Human   101 -LTNVAR------PHRGTWHIQILGFPLRPNRGLYQL-VRATVVYRHHLQLTRFNLSCHVEPWVQ 157

  Fly   756 ----------------------GWQKFDLTDTIRE-WYGHTSHEKLRLLIDC---TGCGGRYSLH 794
                                  .|::.|:|..::: ::.:..|..|||...|   ...||....|
Human   158 KNPTNHFPSSEGDSSKPSLMSNAWKEMDITQLVQQRFWNNKGHRILRLRFMCQQQKDSGGLELWH 222

  Fly   795 LFQTSKLRGNSSDYLSTNPNRPFLVLH---TESS----------------------RTRR----- 829
                    |.||..::      ||:|:   |..|                      |||:
Human   223 --------GTSSLDIA------FLLLYFNDTHKSIRKAKFLPRGMEEFMERESLLRRTRQADGIS 273

  Fly   830 --VRRRAVDCGGALNGQCCKESFYVSFKALGWDDWIIAPRGYFANYCRGDCTGSFR----TPDTF 888
              |...:....|..|.||....|.:||:.||||.|||||..|..|||:|.|....|    :|:
Human   274 AEVTASSSKHSGPENNQCSLHPFQISFRQLGWDHWIIAPPFYTPNYCKGTCLRVLRDGLNSPN-- 336

  Fly   889 QTFHAHFIEEYRKMGLMNGM------RPCCAPIKFSSMSLIYYGDDG-IIKRDLPKMVVDECGC 945
               ||..      ..|:|.:      ||.|.|.|:..:|::....:| |:.::...|:.:.|.|
Human   337 ---HAII------QNLINQLVDQSVPRPSCVPYKYVPISVLMIEANGSILYKEYEGMIAESCTC 391

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Actbeta	NP_651942.2	TGFb_propeptide	370..>509	CDD:279078
		TGF_beta	843..945	CDD:278448	36/112 (32%)
BMP15	NP_005439.2	TGF_beta	291..391	CDD:306518	35/110 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810