Protein Alignment Actbeta and Bmp7

DIOPT Version :10

• Sequence 1: NP_651942.2
• Gene: Actbeta / 43826
• FlyBaseID: FBgn0024913
• Length: 946
• Species: Drosophila melanogaster
• Sequence 2: NP_001178785.1
• Gene: Bmp7 / 85272
• RGDID: 620743
• Length: 430
• Species: Rattus norvegicus
• Alignment Length: 559
• Identity: 124/559 - (22%)
• Similarity: 189/559 - (33%)
• Gaps: 198/559 - (35%)

  Fly   452 RSERDPSHHKY----------RSPF-DFTFNISKNNVYGKVL--RNRSLERIDKKNSFLNGWTEN 503
            ||.|..:.|.:          ||.. ||:.:   |.|:...:  |.||.||.:.:...|:
  Rat     4 RSLRAAAPHSFVALWAPLFLLRSALADFSLD---NEVHSSFIHRRLRSQERREMQREILS----- 60

  Fly   504 RQLKINSQIASMPIELKSH----HNSSPK---ELKSGAVRKVNGINGTQMNENALKKSTYPIDIN 561
                    |..:|...:.|    |||:|.   :|.:....:.:|.:|        :..:||....
  Rat    61 --------ILGLPHRPRPHLQGKHNSAPMFMLDLYNAMAVEESGPDG--------QGFSYPYKAV 109

  Fly   562 HSIDNKTHTGKNGEMSHNDYEYFND-------YSVQTHDKNRYHEGRSSIGYQPAIHNIEYENQK 619
            .|.......      |..|..:..|       .::..|||..:|                   .:
  Rat   110 FSTQGPPLA------SLQDSHFLTDADMVMSFVNLVEHDKEFFH-------------------PR 149

  Fly   620 GHHESFADDHENIDHEDFFGNTQEIITFAEEGTQYRQYR--ILEFSAQNRRVPSQKLSIRSAQIH 682
            .||..|..|...|..       .|.:|.||    :|.|:  |.|      |..::...|...|:
  Rat   150 YHHREFRFDLSKIPE-------GEAVTAAE----FRIYKDYIRE------RFDNETFQITVYQV- 196

  Fly   683 IRIDKPHSLWIEKAKSLPEKHLLNTKRKWGANKPHHRIKIWVFQLSTSINITEKGIDKAIIFRAS 747
                     ..|.:....:..||:::..|.:.:
  Rat   197 ---------LQEHSGRESDLFLLDSRTIWASEE-------------------------------- 220

  Fly   748 FQVDPKNLGWQKFDLTDTIREWYGHTSHEKLRLLIDCTGCGGRYSLHLFQTSKLRGNSSDYLSTN 812
                    ||..||:|.|...|..:..| .|.|.:......|: |::    .||.|....:...|
  Rat   221 --------GWLVFDITATSNHWVVNPRH-NLGLQLSVETLDGQ-SIN----PKLAGLIGRHGPQN 271

  Fly   813 PNRPFLV-------LHTESSRTRRVRRRAVDCGGALNGQ-------------------CCKESFY 851
             .:||:|       :|..|.|:...::|:.:.......|                   |.|...|
  Rat   272 -KQPFMVAFFKATEVHLRSIRSTGGKQRSQNRSKTPKNQEALRMASVAENSSSDQRQACKKHELY 335

  Fly   852 VSFKALGWDDWIIAPRGYFANYCRGDCT---GSFRTPDTFQTFHA------HFIEEYRKMGLMNG 907
            |||:.|||.||||||.||.|.||.|:|.   .|:..    .|.||      |||..      ...
  Rat   336 VSFRDLGWQDWIIAPEGYAAYYCEGECAFPLNSYMN----ATNHAIVQTLVHFINP------DTV 390

  Fly   908 MRPCCAPIKFSSMSLIYYGD-DGIIKRDLPKMVVDECGC 945
            .:|||||.:.:::|::|:.| ..:|.:....|||..|||
  Rat   391 PKPCCAPTQLNAISVLYFDDSSNVILKKYRNMVVRACGC 429

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Actbeta	NP_651942.2	TGF_beta_INHB	845..945	CDD:381630	42/109 (39%)
Bmp7	NP_001178785.1	TGFb_propeptide	35..279	CDD:459906	67/363 (18%)
		TGF_beta_BMP7	324..430	CDD:381667	44/116 (38%)