Protein Alignment Actbeta and Tgfb2

DIOPT Version :10

• Sequence 1: NP_651942.2
• Gene: Actbeta / 43826
• FlyBaseID: FBgn0024913
• Length: 946
• Species: Drosophila melanogaster
• Sequence 2: NP_112393.2
• Gene: Tgfb2 / 81809
• RGDID: 70491
• Length: 442
• Species: Rattus norvegicus
• Alignment Length: 493
• Identity: 104/493 - (21%)
• Similarity: 170/493 - (34%)
• Gaps: 150/493 - (30%)

  Fly   505 QLKINS------QIASMPIELKSHHNSSPKELKSGAVRKVNGINGTQMNENALKKSTYPIDINHS 563
            :||:.|      :...:|.|:.|.:||:...|:..|.|:.......:.:|....|..|.||:...
  Rat    47 KLKLTSPPEDYPEPDEVPPEVISIYNSTRDLLQEKASRRAAACERERSDEEYYAKEVYKIDMPSH 111

  Fly   564 IDNK-------THTGKNGEMSHNDYEYFNDYSVQTHDKNRYHEGRSSIGYQPAIHNIEYENQKGH 621
            ..::       |.:|..|....                   .:.:...||..||
  Rat   112 FPSETVCPVVTTSSGSVGSFCS-------------------RQSQVLCGYLDAI----------- 146

  Fly   622 HESFADDHENIDHEDFFGNTQEIITFAEEGTQYRQY-RILEFSAQNRRVPSQKLSIRSAQIHI-R 684
                                        ..|.||.| ||:.|........:..|.  .|:..: |
  Rat   147 ----------------------------PPTFYRPYFRIVRFDVSTMEKNASNLV--KAEFRVFR 181

  Fly   685 IDKPHSLWIEKAKSLPEKHLLNTKRKWGANKPHHRIKIWVFQLSTSINI---TEKGID-KAIIFR 745
            :..|.:...|:                         :|.::|:..|.::   |::.|| |.:..|
  Rat   182 LQNPKARVAEQ-------------------------RIELYQILKSKDLTSPTQRYIDSKVVKTR 221

  Fly   746 ASFQVDPKNLGWQKFDLTDTIREWYGHTSHE-KLRLLIDCTGC----GGRYSL-HLFQTSKLR-- 802
            |..:       |..||:||.:.||..|.... ..::.:.|..|    ...|.: :..|..:.|
  Rat   222 AEGE-------WLSFDVTDAVHEWLHHKDRNLGFKISLHCPCCTFIPSNNYIIPNKSQELEARFA 279

  Fly   803 --GNSSDYLS------------TNPNRPFLVL------HTESSRTRRVRRRAVD---CGGALNGQ 844
              ..:|.|.|            ::...|.|:|      ..||.::.|.|:||:|   |...:...
  Rat   280 GIDGTSTYASGDQKTIKSTRKKSSGKTPHLLLMLLPSYRLESQQSSRRRKRALDAAYCFRNVQDN 344

  Fly   845 CCKESFYVSFKA-LGWDDWIIAPRGYFANYCRGDCTGSFRTPDTFQTFHAHFIEEYRKMGLMNGM 908
            ||....|:.||. ||| .||..|:||.||:|.|.|...:.:    .|.|...:..|..:......
  Rat   345 CCLRPLYIDFKRDLGW-KWIHEPKGYNANFCAGACPYLWSS----DTQHTKVLSLYNTINPEASA 404

  Fly   909 RPCCAPIKFSSMSLIYY-GDDGIIKRDLPKMVVDECGC 945
            .|||.......::::|| |:...|:: |..|:|..|.|
  Rat   405 SPCCVSQDLEPLTILYYIGNTPKIEQ-LSNMIVKSCKC 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Actbeta	NP_651942.2	TGF_beta_INHB	845..945	CDD:381630	32/101 (32%)
Tgfb2	NP_112393.2	TGFb_propeptide	21..256	CDD:459906	53/300 (18%)
		TGF_beta_TGFB2	345..441	CDD:381655	32/101 (32%)