DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Actbeta and inha

DIOPT Version :9

Sequence 1:	NP_651942.2	Gene:	Actbeta / 43826	FlyBaseID:	FBgn0024913	Length:	946	Species:	Drosophila melanogaster
Sequence 2:	NP_001038669.1	Gene:	inha / 570520	ZFINID:	ZDB-GENE-060503-554	Length:	347	Species:	Danio rerio

Alignment Length:	250	Identity:	63/250 - (25%)
Similarity:	96/250 - (38%)	Gaps:	73/250 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   723 WVFQLST--SINITEKGI----DKAIIFRASFQVDPKNLGWQKFDLTDTIREWYGHT--SHEKLR 779
            |.:...|  ||||:....    :|.::..:...|.....||..:.|     :.:.||  :..:..
Zfish   143 WFYAGETIASINISAPLFILTHNKELLKASESPVKRSPDGWTTYKL-----DVHLHTPMADGQFM 202

  Fly   780 LLIDCTGCGGRYSLHLFQTSKLRGNSSDYLSTNPNRPFLVLHTESSRTRRVRR------------ 832
            |.|.|..|    |.|         :|.|      ..|||.|||.||...|.||
Zfish   203 LQIRCPTC----SCH---------DSED------KTPFLHLHTRSSGPDRSRRAPKIPWSPDAIE 248

  Fly   833 ---RAVDCGGALNGQCCKESFYVSFKALGWDDWIIAPRGYFANYCRGDCTGSFRTPDTFQTFHAH 894
               |....|    ..|.:|...:||:.|||::||:.|:.:...||.|:|:.:
Zfish   249 NLKRPASQG----TDCRREQIEISFEDLGWNNWIVHPKSFTFYYCHGNCSSA------------- 296

  Fly   895 FIEEYRKMGLMNGMRPCCAPIKFSSMSLIY--YGDDGIIKR--DLPKMVVDECGC 945
                 .::..:.|:..||||:..|..||.:  ..|.|...:  .||.::.:||.|
Zfish   297 -----ERITTILGITQCCAPVPESMKSLRFTTTSDGGYSFKYETLPNIIPEECNC 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Actbeta	NP_651942.2	TGFb_propeptide	370..>509	CDD:279078
Actbeta	NP_651942.2	TGF_beta	843..945	CDD:278448	28/105 (27%)
inha	NP_001038669.1	TGF_beta	258..346	CDD:278448	28/105 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11848
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910