Protein Alignment Actbeta and tgfb5

DIOPT Version :9

• Sequence 1: NP_651942.2
• Gene: Actbeta / 43826
• FlyBaseID: FBgn0024913
• Length: 946
• Species: Drosophila melanogaster
• Sequence 2: XP_021336789.1
• Gene: tgfb5 / 559723
• ZFINID: ZDB-GENE-130425-3
• Length: 414
• Species: Danio rerio
• Alignment Length: 433
• Identity: 89/433 - (20%)
• Similarity: 153/433 - (35%)
• Gaps: 115/433 - (26%)

  Fly   585 NDYSVQTHDKNRYHEGRSSI----------------GYQPA------IHNIEYE--NQKGHHESF 625
            :.|::..|...|....|..|                ..||.      ::|...|  .::..|...
Zfish    24 HSYNLDDHKSKRIEAVRGQILSKLRIRSPPDPEASPTPQPVPAEVMLLYNSTKELLKERARHAEA 88

  Fly   626 ADDHENIDHEDFFGNTQEIITF---------AEEGTQYRQYRILEFSAQNRRVPSQKLSIRSAQI 681
            |.:.|: ..||::....:.:..         ...|.|...:||:.|...|  |.....::..|:.
Zfish    89 ACERES-SEEDYYAKEVQRVNMMPLRTDTNSISPGPQSPYFRIVGFDVTN--VERNSSTLVKAEF 150

  Fly   682 HI-RIDKPHSLWIEKAKSLPEKHLLNTKRKWGANKPHHRIKIWVFQLSTSINIT---EKGIDKAI 742
            .| |...|.:...|:                         ::.::|:..|.::|   ::.||
Zfish   151 RIFRAPNPQARATEQ-------------------------RVEIYQILKSEDVTAPSQRYID--- 187

  Fly   743 IFRASFQVDPKNLG-WQKFDLTDTIREWYGHTSHE-KLRLLIDCTGCGGRYSLH----------- 794
                |..|:|:..| |...|:|:|::||....... .|::.:.|..|....|.:
Zfish   188 ----SRTVEPRAKGAWLSVDVTETVKEWMAFRERNLGLKISVHCPCCTFVPSTNNIVPNKSEELE 248

  Fly   795 ---------LFQTSKLRGNSSDYLSTNPNRPFLV--------LHTESSRTRRVRRRAVD---CGG 839
                     |.:.::..|.:...:..:...|.|:        |.:...:||: :|.|.|   |
Zfish   249 ARFAGIDDDLIKQTRKPGVTKGQIEFSTKTPHLILTLLPTDRLDSPIKKTRK-KRSAADTSIC-- 310

  Fly   840 ALNGQ-CCKESFYVSFKA-LGWDDWIIAPRGYFANYCRGDCTGSFRTPDTFQTFHAHFIEEYRKM 902
            ..|.| ||..|.|:.|:. |.| .||..|:||.||:|.|:|...:...:.:..    .:..|.||
Zfish   311 TRNDQGCCLRSLYIDFRRDLNW-KWIHEPKGYKANFCAGNCPYLWSADNHYNM----ILPLYNKM 370

  Fly   903 GLMNGMRPCCAPIKFSSMSLIYYGDDGIIKRDLPKMVVDECGC 945
            .......|||.|.....::::|:.........|..|||..|.|
Zfish   371 NPEASASPCCVPQDLEPLTIVYFLGRTPRVEQLSNMVVRSCKC 413

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Actbeta	NP_651942.2	TGFb_propeptide	370..>509	CDD:279078
		TGF_beta	843..945	CDD:278448	31/103 (30%)
tgfb5	XP_021336789.1	TGFb_propeptide	21..229	CDD:307025	43/239 (18%)
		TGF_beta	317..413	CDD:306518	30/100 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11848
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	5	4.870