DRSC/TRiP Functional Genomics Resources

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Protein Alignment Actbeta and inhbab

DIOPT Version :9

Sequence 1:NP_651942.2 Gene:Actbeta / 43826 FlyBaseID:FBgn0024913 Length:946 Species:Drosophila melanogaster
Sequence 2:NP_001018166.1 Gene:inhbab / 553816 ZFINID:ZDB-GENE-050525-2 Length:405 Species:Danio rerio


Alignment Length:422 Identity:109/422 - (25%)
Similarity:168/422 - (39%) Gaps:114/422 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   549 NALKKSTYPIDINHSID--------NKTHTGKNGEMSHNDYEYFNDYSVQTHDKNRYHEGRSSIG 605
            |.|..:|.| ::.|.:.        .|.|.|:.||                       :|     
Zfish    72 NMLHLNTRP-NVTHPVPRAALLNAIRKPHVGRVGE-----------------------DG----- 107

  Fly   606 YQPAIHNIEYENQKGHHESFADDHENIDHEDFFGNTQEIITFAEEGTQYRQYRILEFSAQNRRVP 670
                  .:|.|...|   ...:..|..:.:.|     |||||||.|.   ...:|:|........
Zfish   108 ------TVEMEEDGG---GLGEHREQPEEQPF-----EIITFAEPGD---APDVLKFDISKEGST 155

  Fly   671 SQKLSIRSAQIHIRIDKPHSLWIEKAKSLPEKHLL-NTKRKWGA-NKPHHRIKIWVFQLSTSINI 733
            ...:...:..:.:::.|.     .:.|......|| |.|...|: ::|..::            :
Zfish   156 LSVVEQANVWLFLKVAKG-----SRVKGKVSVQLLQNGKADSGSTDRPEDQV------------V 203

  Fly   734 TEKGIDKAIIFRASFQVDPKNLGWQKFDLTDTIREWYGHTSHEKLRLLIDCTGCGGRYSLHLF-- 796
            :||            .:|.:..||....:..|::......| ..|.|.:.|..|....::.:.  
Zfish   204 SEK------------TIDTRRSGWHTLPVPRTVQTLLDGDS-SLLSLRVSCPMCAEAGAVPILVP 255

  Fly   797 -QTSKLRGNSSDYLSTNPNRPFL--VLHTESSRTRRVRRRAVDCGGALNGQCCKESFYVSFKALG 858
             :.:|::.....:      ||||  ||........|..:|.::|.|.:. .|||..|||:||.:|
Zfish   256 AEGNKVKEREQSH------RPFLMVVLKPAEEHQHRRSKRGLECDGKIR-VCCKRQFYVNFKDIG 313

  Fly   859 WDDWIIAPRGYFANYCRGDC-------TGSFRTPDTFQTFHAHFIEEYRKMGL--MNGMRPCCAP 914
            |.||||||.||.||||.|||       |||      ..:||:..|..||..|.  .|.::.||.|
Zfish   314 WSDWIIAPSGYHANYCEGDCPSHVASITGS------ALSFHSTVINHYRMRGYSPFNNIKSCCVP 372

  Fly   915 IKFSSMSLIYYGDD-GIIKRDLPKMVVDECGC 945
            .:..:||::||.:: .|||:|:..|:||||||
Zfish   373 TRLRAMSMLYYNEEQKIIKKDIQNMIVDECGC 404

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ActbetaNP_651942.2 TGFb_propeptide 370..>509 CDD:279078
TGF_beta 843..945 CDD:278448 51/111 (46%)
inhbabNP_001018166.1 TGFb_propeptide 64..272 CDD:279078 48/281 (17%)
TGF_beta 298..404 CDD:278448 51/112 (46%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 121 1.000 Domainoid score I5640
eggNOG 1 0.900 - - E1_KOG3900
Hieranoid 00.000 Not matched by this tool.
Homologene 1 1.000 - - H1653
Inparanoid 1 1.050 190 1.000 Inparanoid score I3867
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1385831at2759
OrthoFinder 1 1.000 - - FOG0000887
OrthoInspector 1 1.000 - - otm24667
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR11848
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R4608
SonicParanoid 1 1.000 - - X477
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
1111.000

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