Protein Alignment Actbeta and nodal1

DIOPT Version :9

• Sequence 1: NP_651942.2
• Gene: Actbeta / 43826
• FlyBaseID: FBgn0024913
• Length: 946
• Species: Drosophila melanogaster
• Sequence 2: NP_001016321.1
• Gene: nodal1 / 549075
• XenbaseID: XB-GENE-487169
• Length: 403
• Species: Xenopus tropicalis
• Alignment Length: 430
• Identity: 97/430 - (22%)
• Similarity: 162/430 - (37%)
• Gaps: 147/430 - (34%)

  Fly   593 DKNRYHEGRSSIGYQPAIH-NIEYENQKG---HHESFADDHENIDHEDFFGNTQEIITFAEEGTQ 653
            |.||:|.......|...:: |:...|..|   .|.:...:::.:           :..||:...:
 Frog    43 DGNRHHRDMKYPFYMMQLYQNLVMANDTGLARGHNTATKEYDTV-----------LSLFAKRCME 96

  Fly   654 YRQYRILEFSAQNRRVPSQKLSIRSAQIHIRIDKPHSLWIEKAKSLPEKHLLNTKRKWGANKPHH 718
            ..:...|.|   :....|:...::.|:  :||..||   ||.:                     |
 Frog    97 SEKRWTLSF---DMSAVSKSSELKLAE--LRIQLPH---IEMS---------------------H 132

  Fly   719 RIKIWVFQLSTSINITEKGIDKAIIFRASFQVDP---KNLGWQKFDLTDTIREWY---------- 770
            .:.:.|:.       |..|.:.  ::..||:.:|   |...|:.|::|..::.::
 Frog   133 NVTVDVYH-------TRDGEEN--LYLGSFEANPFSTKGSPWKVFNVTRILQHYFKEGQDIKSEY 188

  Fly   771 -----------GHTSHEKLRLLIDCTGCGGRYSLHLFQTSKLRGNSSDYLST-----------NP 813
                       |.:|.|    .:|..|...:|:.|   .:.||    .||||           .|
 Frog   189 LRTKDRAERGSGMSSAE----FLDSPGDSPQYNPH---HTPLR----RYLSTEGVMLVLFTKVKP 242

  Fly   814 N-----RPFLVLHTESSR------------TRRVRR---------------RAVDCGGALNGQCC 846
            :     .|.|:...|||:            .||.||               |.||.|..|   |.
 Frog   243 SVNHIGFPSLIKTAESSKYVDMEKASRMPGIRRHRRNKNEKHHLSMGSIPSRHVDNGKPL---CR 304

  Fly   847 KESFYVSFKALGWDDWIIAPRGYFANYCRGDCTGSFRTPDTFQ-TFHAHF---IEEYR--KMGLM 905
            :....|:|:.:||.:||:.|:.|.|..|.|.|  .....:||: |.||:.   ::.|:  |:..
 Frog   305 RVDMIVNFEDIGWGNWIVYPKKYNAYRCEGAC--PIPLNETFKPTNHAYMKSVVKLYQPEKVEC- 366

  Fly   906 NGMRPCCAPIKFSSMSLIYYGDDGIIKRDLPKMVVDECGC 945
                |.|.|||.|.:|::||..|.::.|...:|:|:||||
 Frog   367 ----PLCVPIKMSPLSMLYYEGDEVVLRHHQEMIVEECGC 402

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Actbeta	NP_651942.2	TGFb_propeptide	370..>509	CDD:279078
		TGF_beta	843..945	CDD:278448	35/107 (33%)
nodal1	NP_001016321.1	TGFb_propeptide	46..218	CDD:279078	36/224 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	195..220		7/31 (23%)
		TGFB	303..403	CDD:214556	37/107 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000