Protein Alignment Actbeta and Gdf3

DIOPT Version :10

• Sequence 1: NP_651942.2
• Gene: Actbeta / 43826
• FlyBaseID: FBgn0024913
• Length: 946
• Species: Drosophila melanogaster
• Sequence 2: NP_001103141.1
• Gene: Gdf3 / 500311
• RGDID: 1564178
• Length: 366
• Species: Rattus norvegicus
• Alignment Length: 322
• Identity: 79/322 - (24%)
• Similarity: 140/322 - (43%)
• Gaps: 57/322 - (17%)

  Fly   635 EDFFGNTQEIITFAEEGTQYRQYRILEFSAQNRRVPSQKLSIRSAQIHIRIDKPHSLWIEKAKSL 699
            :.||.|||:.   :::|:..::......||...:   .||::....:|:.....|.|.:|...::
  Rat    90 QGFFLNTQKP---SQDGSCLQKVLSFNLSAVKEK---GKLTMAQLILHLGPRSYHYLQLELVVAV 148

  Fly   700 PEKHLLNTKRKWGANKPHHRIKIWVFQLSTSINITEKGIDKAIIFRASFQVDPKNLGWQKFDLTD 764
               .::..:..||.:.|         :|...:      :.|:::       .|:  |..:|:|..
  Rat   149 ---SVVQDRGVWGRSHP---------KLGRLL------VQKSVL-------GPQ--GSLQFNLQG 186

  Fly   765 TIREWYGHTSHEKLRLLIDCTGCGGRYSLHLFQTSKLRGNSSDYLSTNPNRPFLVL-----HTES 824
            .:::|..| ..:.|.|.::......|||    :.:....|..:.|..:.:...||:     |...
  Rat   187 VVKDWNRH-QLKNLDLYLEILVKEDRYS----RVNAQLDNPCNQLMHSLHASLLVVTLNLKHCHP 246

  Fly   825 SRTRRVRRRAVDC-GGALNGQCCKESFYVSFKALGWDDWIIAPRGYFANYCRGDCTGSFRTPDTF 888
            |  .|.:|.|:.. .|.....|.:...:|:|:.|||..|:|||:|:.||||.|||      |.|.
  Rat   247 S--SRKKRAAIPIPKGLCRNLCHRHQLFVNFQDLGWHKWVIAPKGFMANYCHGDC------PFTM 303

  Fly   889 QTF----HAHFIEEYRKMGLMNGMRPCCAPIKFSSMSLIYYGDD-GIIKRDLPKMVVDECGC 945
            .|:    :..|::....|......:..|.|.|.|.:|::|..:: .:|.|....||||||||
  Rat   304 TTYLNSSNYAFMQALMHMADPRVPKAVCIPTKLSPISMLYQDNEKNVILRHYEDMVVDECGC 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Actbeta	NP_651942.2	TGF_beta_INHB	845..945	CDD:381630	37/104 (36%)
Gdf3	NP_001103141.1	TGFb_propeptide	24..204	CDD:480997	27/147 (18%)
		TGF_beta_SF	266..366	CDD:477357	39/106 (37%)