Protein Alignment Actbeta and Lefty1

DIOPT Version :10

• Sequence 1: NP_651942.2
• Gene: Actbeta / 43826
• FlyBaseID: FBgn0024913
• Length: 946
• Species: Drosophila melanogaster
• Sequence 2: NP_001102550.1
• Gene: Lefty1 / 498299
• RGDID: 1561867
• Length: 368
• Species: Rattus norvegicus
• Alignment Length: 311
• Identity: 68/311 - (21%)
• Similarity: 111/311 - (35%)
• Gaps: 77/311 - (24%)

  Fly   659 ILEFSAQNRRVPSQKLSIRSAQIHIRIDKPHSLWIEKAKSLPEKHLLNTKRKWGANKPHH---RI 720
            :|.|..:.|..|:.:|    .|..:|:.:         :.:|...|...||.    .||.   |:
  Rat    98 LLVFGMEQRLPPNSEL----VQAVLRLFQ---------EPVPRTALRRQKRL----SPHSARARV 145

  Fly   721 KI-WVFQLSTSINITEKGIDKAIIFRASFQVDPKNLGWQKFDLTDTIREWYGHTSHEKLRLLIDC 784
            .| |       :...|.|.::..:..:.. |.....||:.||:|:.:..|. ..|..:..||:..
  Rat   146 TIEW-------LRFREDGSNRTALIDSRL-VSIHESGWKVFDVTEAVNFWQ-QLSRPRQPLLLQV 201

  Fly   785 T------GCGGRYSLHLFQTSKLRGNSSDYLSTNPNRPFLVLHTESSRTRRVRRRAVDCGGALN- 842
            :      | .|.:|.|.......:|...   ......|.|.|||...:         |.|...|
  Rat   202 SVQREHLG-PGTWSAHKLVRFAAQGTPD---GKGLGEPQLELHTLDLK---------DYGAQGNC 253

  Fly   843 ---------GQCCKESFYVSFKALGW-DDWIIAPRGYFANYCRGDCTGSFRTPDTFQTFHAHFIE 897
                     .:||::..|:..:.:.| ::||:.|.|:....|.|.|   .:.|::. |....|:
  Rat   254 DPETPVTEGTRCCRQEMYLDLQGMKWAENWILEPPGFLTYECVGSC---LQPPESL-TIRWPFL- 313

  Fly   898 EYRKMGLMNGMRPCCAPIKFSSMSLIYYGDDGIIKR---DLPKMVVDECGC 945
                     |.|.|.|....|...::...:||..:.   .||.|.|..|.|
  Rat   314 ---------GPRQCVASEMTSLPLIVSIKEDGRTRPQVVSLPNMRVQRCSC 355

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Actbeta	NP_651942.2	TGF_beta_INHB	845..945	CDD:381630	26/103 (25%)
Lefty1	NP_001102550.1	TGFb_propeptide	<62..203	CDD:480997	28/130 (22%)
		TGF_beta_LEFTY1_2	264..355	CDD:381636	26/104 (25%)