Protein Alignment Actbeta and myo

DIOPT Version :10

• Sequence 1: NP_651942.2
• Gene: Actbeta / 43826
• FlyBaseID: FBgn0024913
• Length: 946
• Species: Drosophila melanogaster
• Sequence 2: NP_726604.1
• Gene: myo / 43811
• FlyBaseID: FBgn0026199
• Length: 598
• Species: Drosophila melanogaster
• Alignment Length: 731
• Identity: 156/731 - (21%)
• Similarity: 248/731 - (33%)
• Gaps: 254/731 - (34%)

  Fly   297 INCNGISSSNYYASNLESHKGCTLCHESGKPNIYTDKDNP---------------HTDYNIY--- 343
            :|.|.|.....|..||:|.|     ...|:.||...|...               .|..|.|
  Fly    39 VNSNEIQFPGSYRFNLDSKK-----INIGRMNILGHKRGNFRVTRYVTVTVLLILSTAVNAYAQP 98

  Fly   344 -NKYHSNNNFNKKTNQPHNNIAPSDEVRLESIKRQILTKLGLSHKPNVSHPLPKQFIWETIYRVD 407
             ||..||::         ||.:|.              .:.||::.|.|
  Fly    99 ENKSFSNSS---------NNDSPE--------------MVMLSNETNNS---------------- 124

  Fly   408 GGRMIPNNAFGSSGKNLDQKTIKLRAFASPGSHLFNGRGGRTDQRSERDPSHHKYRSPFDFTFNI 472
              ..:.:...|||..:.|.|              .|...|....:.:..|.
  Fly   125 --AKVLSEKNGSSSISADDK--------------INENMGIFQMKVQSKPG-------------- 159

  Fly   473 SKNNVYGKVLRNRSLERIDK----KNSFLNGWTEN---RQLKINSQIAS-----MPIELKSHHNS 525
            .|:....||..:..|.|:..    :|:.:|  .|:   |||:..:::.|     |.|.::.:...
  Fly   160 KKSTPLAKVSEHGDLSRVQSVSLYRNTLIN--IESMLQRQLREKAKVDSIESIKMHILMRLNLKK 222

  Fly   526 SPKELKSGAVRKVNGINGTQMNENALKKSTY-----PIDINHSIDNKTH----------TGKNGE 575
            .|...|..:|.: |.|:....:.||..|:|.     .||.:|...|.|:          ...:.:
  Fly   223 LPNITKPISVPQ-NIIDNFYRDYNASSKTTVWNRMESIDESHLSINDTYGDHIMTDFFDESSSSQ 286

  Fly   576 MSHNDYEYFNDYSVQTHDKNRYHEGRSSIGYQPAIHNIEYENQKGHHESFADDHENIDHEDFFGN 640
            |..:|....|::.:   |.|:....:|.|   |...|.|                  ::|....:
  Fly   287 MQGDDANTVNEFLI---DLNKNQAKKSDI---PINTNDE------------------EYESILSH 327

  Fly   641 TQEIITFAEEGTQYRQYRILEFSAQNRRVPSQKLSIRS-------AQIHIRI---DKPHSLWI-- 693
            ...|..|.||        |......||:|...:..|.|       |.:|:.:   |     ||
  Fly   328 ISSIYIFPEE--------IQPHVRHNRKVDVFRFQIDSSYSDLSYATLHLYLRGWD-----WISA 379

  Fly   694 ------EKAKSLPEKHLLNTKRKWGANKPHHRIKIWVFQLSTSINITEKGIDKAIIFRASFQVDP 752
                  |:.|..|.|.::.|        .|..|::   ..:||.|...|..:    ||.|.   |
  Fly   380 HQPGLLEEIKKQPRKDIVVT--------IHRAIRV---ANTTSFNPKVKMFE----FRHSI---P 426

  Fly   753 KNLG-WQKFDLTDTIREWYGHTSHEKLRLLIDCTGCGGRYSLHLFQTSKLRGN---------SSD 807
            ..|| |...||...:                      |....::.|...::|.         ::|
  Fly   427 SGLGQWVAVDLKSLL----------------------GNLGSNMTQEILIKGAETWMKSLVVTTD 469

  Fly   808 YLSTNPNRPFLVLHTE-SSRTRRVRRRAV--DC-GGALNGQCCKESFYVSFKALGWDDWIIAPRG 868
            ..|.||    |.:|.| .|:.:..|:|:|  || ....:.:||:....|:|.:.|| .:::||..
  Fly   470 NTSKNP----LTVHIEIGSQKKHRRKRSVYMDCTENDHDMRCCRYPLKVNFTSFGW-HFVVAPTS 529

  Fly   869 YFANYCRGDCTGSFRTPDTFQTFHAHFIEEY---RKMGLMNGMRPCCAPIKFSSMSLIYYGDD-G 929
            :.|.:|.|||             ...::|:|   ....|.....|||:|.|.||:||:|:.|: .
  Fly   530 FDAYFCSGDC-------------KVGYLEQYPHTHLAALTTSATPCCSPTKMSSLSLLYFDDNHN 581

  Fly   930 IIKRDLPKMVVDECGC 945
            ::...:|.|.|:.|.|
  Fly   582 LVLSVIPNMSVEGCSC 597

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Actbeta	NP_651942.2	TGF_beta_INHB	845..945	CDD:381630	31/103 (30%)
myo	NP_726604.1	TGF_beta_GDF8_like	506..597	CDD:381629	31/104 (30%)