Protein Alignment Actbeta and bmp5

DIOPT Version :10

• Sequence 1: NP_651942.2
• Gene: Actbeta / 43826
• FlyBaseID: FBgn0024913
• Length: 946
• Species: Drosophila melanogaster
• Sequence 2: NP_957345.1
• Gene: bmp5 / 394026
• ZFINID: ZDB-GENE-040426-1413
• Length: 446
• Species: Danio rerio
• Alignment Length: 526
• Identity: 115/526 - (21%)
• Similarity: 183/526 - (34%)
• Gaps: 153/526 - (29%)

  Fly   472 ISKNNVYG----KVLRNRSLERIDKKNSFLNGWTEN-RQLKINSQIASMPIELKSHHNSSPKELK 531
            :..|:|:.    :.|||.....|.::...:.|.... |......|.:|.|:.:...:|:...|
Zfish    21 LGDNHVHSSFIYRRLRNHERREIQREILSILGLPHRPRPFSPGKQASSAPLFMLDLYNAMTTE-- 83

  Fly   532 SGAVRKVNGINGTQMNENALKKSTYPIDINHSIDNKTHTGKNGEMSHNDYEYFNDYSVQTHDKNR 596
                           .|||:        :..|:..|......|               ..|..:|
Zfish    84 ---------------EENAI--------LGKSLAGKVRKSAPG---------------APHGYSR 110

  Fly   597 --------YHEGRSSIGYQ-PAIHNIEYENQKGHHESFADDHENIDHEDFFGNTQEIITFAEEGT 652
                    .|...:.:..| |.:.|       .|..:|.:|.:.:  ..|....:....|:....
Zfish   111 APPRVPQPQHSRAAPLSSQSPPLAN-------AHDTNFLNDADMV--MSFVNLVERDKDFSHHRR 166

  Fly   653 QYRQYRI-LEFSAQNRRVPSQKLSIRSAQIHIRIDKPHSLWIEKAKSLPEKHLLNTKRKWGANKP 716
            .||::|. |....:...|.:.:..|...|.|||.:
Zfish   167 HYREFRFDLTQIPEGEAVTAAEFRIYKDQSHIRYE------------------------------ 201

  Fly   717 HHRIKIWVFQLSTSINITE---KGIDKAIIFRASFQVDPKNL-----GWQKFDLTDTIREWYGHT 773
            :..:|:.::|:     |.|   :..|       :|.:|.|.:     ||..||:|.|...|..:.
Zfish   202 NITLKVTIYQV-----IKEYPNRDPD-------TFLLDWKKIRATDGGWLVFDITATSNHWVLNP 254

  Fly   774 SHEK-LRLLIDCT----------GCGGR--------YSLHLFQTSK-----LRGNSSDYLSTNPN 814
            .... |:|.::.|          |..||        :.:..|:.|:     :|...|...|.|.|
Zfish   255 QQNMGLQLCVETTDGRSINMKSAGIIGRNGPQSKQPFLVAFFKASEVLLRSVRATGSKKKSHNRN 319

  Fly   815 RPFLVLHTESSRTRRVRRRAVDCGGALNGQ----CCKESFYVSFKALGWDDWIIAPRGYFANYCR 875
            :         |:|:.....|:..|.....:    |.|...||||:.|||.||||||.||.|.||.
Zfish   320 K---------SKTQVKSTPALKSGDQNTSEQRQACKKHELYVSFRDLGWQDWIIAPEGYAAFYCD 375

  Fly   876 GDCTGSFRTPDTFQTFHAHFIEEYRKMGLMNGMRPCCAPIKFSSMSLIYYGD-DGIIKRDLPKMV 939
            |:|:..... ....|.||........|...|..:|||||.|.:::|::|:.| ..:|.:....||
Zfish   376 GECSFPLNA-HMNATNHAIVQTLVHLMFPDNVPKPCCAPTKLNAISVLYFDDSSNVILKKYRNMV 439

  Fly   940 VDECGC 945
            |..|||
Zfish   440 VRSCGC 445

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Actbeta	NP_651942.2	TGF_beta_INHB	845..945	CDD:381630	41/100 (41%)
bmp5	NP_957345.1	TGFb_propeptide	24..295	CDD:459906	61/361 (17%)
		TGF_beta_BMP5	334..446	CDD:381665	44/113 (39%)