Protein Alignment Actbeta and INHBC

DIOPT Version :10

• Sequence 1: NP_651942.2
• Gene: Actbeta / 43826
• FlyBaseID: FBgn0024913
• Length: 946
• Species: Drosophila melanogaster
• Sequence 2: NP_005529.1
• Gene: INHBC / 3626
• HGNCID: 6068
• Length: 352
• Species: Homo sapiens
• Alignment Length: 309
• Identity: 80/309 - (25%)
• Similarity: 131/309 - (42%)
• Gaps: 60/309 - (19%)

  Fly   643 EIITFAEEGTQYRQYRILEFSAQNRRVPSQKLSIRSAQIHIRIDKP-HSLWIEKAKSLPEKHLLN 706
            |||:|||.|........|:|...:.|....: .::.|.:...:..| ::.|..|.:.|    :|.
Human    97 EIISFAETGLSTINQTRLDFHFSSDRTAGDR-EVQQASLMFFVQLPSNTTWTLKVRVL----VLG 156

  Fly   707 TKRKWGANKPHHRIKIWVFQLSTSINITEKGIDKAIIFRASFQVDPKNLGWQKFDLTDTIREWYG 771
                     ||          :|::.:..:.:         .:||..  ||.:..|....:....
Human   157 ---------PH----------NTNLTLATQYL---------LEVDAS--GWHQLPLGPEAQAACS 191

  Fly   772 HTSHEKLRLLIDCTGCGGRYSLHLFQTSKLRGNSSDYLSTNPNRPFLVLHTESSRTRRVRRRAVD 836
            . .|..|.|:::     |:.:    |:|.:.|.::       :|||:..........::.||.:|
Human   192 Q-GHLTLELVLE-----GQVA----QSSVILGGAA-------HRPFVAARVRVGGKHQIHRRGID 239

  Fly   837 CGGALNGQCCKESFYVSFKALGWDDWIIAPRGYFANYCRGDC----TGSFRTPDTFQTFHAHFIE 897
            |.|. :..||::.|:|.|:.:||.||||.|.||..|:|.|.|    .|......:|.|...:.::
Human   240 CQGG-SRMCCRQEFFVDFREIGWHDWIIQPEGYAMNFCIGQCPLHIAGMPGIAASFHTAVLNLLK 303

  Fly   898 EYRKMGLMNGMRPCCAPIKFSSMSLIYYG-DDGIIKRDLPKMVVDECGC 945
            .....|...| ..||.|.....:||:||. |..|:|.|:|.|||:.|||
Human   304 ANTAAGTTGG-GSCCVPTARRPLSLLYYDRDSNIVKTDIPDMVVEACGC 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Actbeta	NP_651942.2	TGF_beta_INHB	845..945	CDD:381630	39/104 (38%)
INHBC	NP_005529.1	TGF_beta_INHBC_E	247..352	CDD:381676	41/106 (39%)