Protein Alignment Actbeta and INHA

DIOPT Version :9

• Sequence 1: NP_651942.2
• Gene: Actbeta / 43826
• FlyBaseID: FBgn0024913
• Length: 946
• Species: Drosophila melanogaster
• Sequence 2: NP_002182.1
• Gene: INHA / 3623
• HGNCID: 6065
• Length: 366
• Species: Homo sapiens
• Alignment Length: 414
• Identity: 85/414 - (20%)
• Similarity: 123/414 - (29%)
• Gaps: 171/414 - (41%)

  Fly   605 GYQPAIHNIEYENQKG---HHESFADDHENIDHEDFF--------------GNTQEIITFAEEGT 652
            |..|.:..:...:..|   |..|..::.|::.....|              |..||    ||||.
Human    50 GGDPGVRRLPRRHALGGFTHRGSEPEEEEDVSQAILFPATDASCEDKSAARGLAQE----AEEGL 110

  Fly   653 QYRQYRILEFSAQNRRVPSQ---KLSIRSAQI--HIRIDKPHSLWIEKAKSLPEKHLLN------ 706
            ....:|           |||   ...:.|||:  |..:|:..:     |.|...:.||.
Human   111 FRYMFR-----------PSQHTRSRQVTSAQLWFHTGLDRQGT-----AASNSSEPLLGLLALSP 159

  Fly   707 -----TKRKWGANKPHHRIKIW-VFQLSTSINITEKGIDKAIIFRASFQVDPKNLGWQKFDLTDT 765
                 .....|...||     | |..|:||.
Human   160 GGPVAVPMSLGHAPPH-----WAVLHLATSA---------------------------------- 185

  Fly   766 IREWYGHTSHEKLRLLIDCTGCGGRYSLHLFQTSKLRGNSSDYLSTNPNRPFLVLHTESSRTR-- 828
                ....:|..|.||:.|..|          |...|..::         ||||.||   |||
Human   186 ----LSLLTHPVLVLLLRCPLC----------TCSARPEAT---------PFLVAHT---RTRPP 224

  Fly   829 ----RVRRRAVDCG-----------------GALNGQCCKESFYVSFKALGWDDWIIAPRGYFAN 872
                |.||......                 .|.:..|.:.:..:||:.|||:.||:.|..:..:
Human   225 SGGERARRSTPLMSWPWSPSALRLLQRPPEEPAAHANCHRVALNISFQELGWERWIVYPPSFIFH 289

  Fly   873 YCRGDC------------TGSFRTPDTFQTFHAHFIEEYRKMGLMNGMRPCCAPIKFSSMSL-IY 924
            ||.|.|            .|:..||          .:.|   .|:.|.:||||.:..:...| :.
Human   290 YCHGGCGLHIPPNLSLPVPGAPPTP----------AQPY---SLLPGAQPCCAALPGTMRPLHVR 341

  Fly   925 YGDDG---IIKRDLPKMVVDECGC 945
            ...||   .....:|.::...|.|
Human   342 TTSDGGYSFKYETVPNLLTQHCAC 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Actbeta	NP_651942.2	TGFb_propeptide	370..>509	CDD:279078
		TGF_beta	843..945	CDD:278448	28/117 (24%)
INHA	NP_002182.1	TGFB	262..366	CDD:214556	29/117 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11848
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.910