DRSC/TRiP Functional Genomics Resources

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Protein Alignment Actbeta and bmp2a

DIOPT Version :9

Sequence 1:NP_651942.2 Gene:Actbeta / 43826 FlyBaseID:FBgn0024913 Length:946 Species:Drosophila melanogaster
Sequence 2:NP_571434.1 Gene:bmp2a / 30631 ZFINID:ZDB-GENE-980526-388 Length:386 Species:Danio rerio


Alignment Length:379 Identity:90/379 - (23%)
Similarity:140/379 - (36%) Gaps:124/379 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   656 QYRILE-FSAQNRRVPSQKLSIRSAQIHIRIDKPHSLWIEKAKSLPEKHL----------LNTKR 709
            :.|:|. |..|:|..||....:  .|..:.:...||:..|:. |.|..||          .||.|
Zfish    42 ELRLLSMFGLQHRPTPSTSAVV--PQYMLDLYSAHSVNAEQV-SRPRAHLGKGSERSASRANTIR 103

  Fly   710 KWGANKPHH----------------------------------RIKIWVFQLSTSINITEKGIDK 740
            .:     ||                                  .::::..|:.:|:|....|..:
Zfish   104 SF-----HHDESTEDPSSSSVRTTQRFLFNLTSIPDEELVTSADVRVFREQIVSSLNNASAGFHR 163

  Fly   741 AIIFR-----ASFQ-----------VDPKNLGWQKFDLTDTIREWY--GHTSHEKLRLLIDCTGC 787
            ..:..     .|.|           |......|:.||:|..:.:|.  ||.:|   .:|::.:  
Zfish   164 INVHEIIRPSGSLQEPITRLLDTRLVQHSLSKWESFDVTPAVLKWTTDGHPNH---GILVEIS-- 223

  Fly   788 GGRYSLHLFQTSKLRGNSSDYLSTNPN-----RPFL----------VLHTESSR-----TRRVRR 832
                  |..|.|:.....|..|..|.:     ||.|          |||:...|     .:|.:.
Zfish   224 ------HPDQDSRKHVRVSRSLHNNEDTWSQMRPLLVTYSHDGKGNVLHSREKRQARNNKQRKKH 282

  Fly   833 RAVDCGGALNGQCCKESFYVSFKALGWDDWIIAPRGYFANYCRGDCTGSFRTPDTFQTFHAHFIE 897
            :|         .|.:.|.||.|..:||:|||:||.||.|.||:|:|  .|...|     |.:...
Zfish   283 KA---------NCRRHSLYVDFSDVGWNDWIVAPPGYHAFYCQGEC--PFPLAD-----HLNSTT 331

  Fly   898 EYRKMGLMNGM-----RPCCAPIKFSSMSLIYYGD-DGIIKRDLPKMVVDECGC 945
            ......|:|.:     |.||.|...|.:||:|..: :.:|.::...|||:.|||
Zfish   332 NAMVQTLVNSVNSNIPRACCVPTDLSPVSLLYLDEYERVILKNYQDMVVEGCGC 385

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ActbetaNP_651942.2 TGFb_propeptide 370..>509 CDD:279078
TGF_beta 843..945 CDD:278448 37/107 (35%)
bmp2aNP_571434.1 TGFb_propeptide 28..256 CDD:279078 45/232 (19%)
TGFB 286..386 CDD:214556 39/107 (36%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3900
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

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