Protein Alignment Actbeta and lft2

DIOPT Version :10

• Sequence 1: NP_651942.2
• Gene: Actbeta / 43826
• FlyBaseID: FBgn0024913
• Length: 946
• Species: Drosophila melanogaster
• Sequence 2: NP_571036.1
• Gene: lft2 / 30146
• ZFINID: ZDB-GENE-990630-11
• Length: 362
• Species: Danio rerio
• Alignment Length: 425
• Identity: 103/425 - (24%)
• Similarity: 158/425 - (37%)
• Gaps: 132/425 - (31%)

  Fly   559 DINHSIDNKTHTGKNGEMSHNDYEYFNDYSVQTHDKNRY-------HE-GRSSIGYQPAIHNIEY 615
            ||..::..|....:...:...|.|   :..|..|.|::|       |: .|.|:   |::..|
Zfish    24 DIKQALLQKLGLTEPPRIQKRDLE---NLVVPAHIKSKYLSMLKLHHQRRRRSL---PSLAGI-- 80

  Fly   616 ENQKGHHESFADDHENIDHEDFFGNTQEIITFAEEGTQYRQYRILEFSAQNRRVPSQKLSI--RS 678
              .:|.|.: ||....|.:.|   .|::.:.|..|.      |:.|    |..|...:|.:  .:
Zfish    81 --LRGIHGN-ADITGEIKYSD---TTRQRLVFDMEA------RLQE----NTEVTMAELKLFQTA 129

  Fly   679 AQIHIRIDKPHSLWIEKAKSLPEKHLLNTKRKWGANKP--HHRIKI-WVFQLSTSINITEKGIDK 740
            ||               :.|.||:.         .::|  |.|:.| ||..|....|.|.....:
Zfish   130 AQ---------------SPSKPERR---------HHRPINHARVSIYWVEVLENGSNRTSLLDSR 170

  Fly   741 AIIFRASFQVDPKNLGWQKFDLTDTIREWYGHTSHEKLRLLIDCTGCG---GRYSLHL-----FQ 797
            .:....|        ||:.||:|..|..|  ..|.:|..|.::....|   |.|:..:     |.
Zfish   171 LVPIHES--------GWRSFDVTQAIHYW--SKSQKKAPLHLEVWTEGERPGSYAAEMAKRVRFA 225

  Fly   798 TSKLRGNSSDYLSTNPNRPFLVLHTESSRTRRVRRRAVD---------CGGALN-GQCCKESFYV 852
            |...:.|:   |..:...|.|||:|            :|         |..:.| .:||:|..::
Zfish   226 TQDPKENT---LEKDMGAPELVLYT------------LDLDEYGSQGNCNSSPNSSKCCREEHFI 275

  Fly   853 SFKALGWDD-WIIAPRGYFANYCRGDCTGSFRTPDTFQTFHAHFIEEYRKMGLMN-GMRPCC--- 912
            :|:.|.|.. |||.|.||.|..|.|.|    :.|               |.|... |.|.|.
Zfish   276 NFRELTWTQYWIIEPAGYQAFRCAGGC----KQP---------------KRGFYGYGQRTCAVME 321

  Fly   913 -APIKFSSMSLIYYGDDGIIK-RDLPKMVVDECGC 945
             ||:..  |.|:..||...|: .:.|.|:|::|||
Zfish   322 SAPLPM--MYLVKKGDYTEIEVAEFPNMIVEKCGC 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Actbeta	NP_651942.2	TGF_beta_INHB	845..945	CDD:381630	33/106 (31%)
lft2	NP_571036.1	TGFb_propeptide	23..>191	CDD:480997	49/222 (22%)
		TGF_beta_LEFTY1_2	267..354	CDD:381636	33/107 (31%)