Protein Alignment Actbeta and Bmp6

DIOPT Version :9

• Sequence 1: NP_651942.2
• Gene: Actbeta / 43826
• FlyBaseID: FBgn0024913
• Length: 946
• Species: Drosophila melanogaster
• Sequence 2: XP_038951315.1
• Gene: Bmp6 / 25644
• RGDID: 2214
• Length: 535
• Species: Rattus norvegicus
• Alignment Length: 648
• Identity: 135/648 - (20%)
• Similarity: 215/648 - (33%)
• Gaps: 265/648 - (40%)

  Fly   374 IKRQILTKLGLSHKPNVSHPLPKQFIWETIYRVDGGRMIPNNAFGSSGKNLDQKTIKLRAFASPG 438
            ::::||:.|||.|:|...|.|.:                |.:..      |.|:.
  Rat    76 MQKEILSVLGLPHRPRPLHGLQQ----------------PQSPV------LPQQQ---------- 108

  Fly   439 SHLFNGRGGRTDQRSERDPSHHKYRSPFDFTFNISKNNVYGKVLRNRSLERIDKKNSFLNGWTEN 503
                     ::.|.:..:|...:.:|...|..::           ..||.:.|::    :|.:|.
  Rat   109 ---------QSQQTAREEPPPGRLKSAPLFMLDL-----------YNSLSKDDEE----DGVSEG 149

  Fly   504 RQLKINSQIASMPIELKSHHNSSPKELKS---GAVRKVNGINGTQMNENALKKSTYPIDINHSID 565
            ..|           |.:||..:|..:||.   ||.                          ||::
  Rat   150 EGL-----------EPESHGRASSSQLKQPSPGAA--------------------------HSLN 177

  Fly   566 NKT--HTGKNGE----MSHNDYEYFND-------YSVQTHDKNRYHEGRSSIGYQPAIHNIEYEN 617
            .|:  ..|..|.    .|..|..:.||       .::..:||                   |:..
  Rat   178 RKSLLAPGPGGSASPLTSAQDSAFLNDADMVMSFVNLVEYDK-------------------EFSP 223

  Fly   618 QKGHHESFADDHENIDHEDFFGNTQEIITFAEEGTQYRQYR---ILEFSAQNRRVPSQKLSIRSA 679
            ::.||:.|..:...|..       .|.:|.||    :|.|:   :..|..|...:...::    .
  Rat   224 RQRHHKEFKFNLSQIPE-------GEAVTAAE----FRVYKDCVVGSFKNQTFLISIYQV----L 273

  Fly   680 QIHIRIDKPHSLWIEKAKSLPEKHLLNTKRKWGANKPHHRIKIWVFQLSTSINITEKGIDKAIIF 744
            |.|...|.             :..||:|:..|.:.:
  Rat   274 QEHQHRDS-------------DLFLLDTRVVWASEE----------------------------- 296

  Fly   745 RASFQVDPKNLGWQKFDLTDTIREWYGHTSHEK-LRLLIDCTGCGGRYSLHLF-QTSKLRGNSSD 807
                       ||.:||:|.|...|.....|.. |:|.:..     |..||:. :.:.|.|....
  Rat   297 -----------GWLEFDITATSNLWVVTPQHNMGLQLSVVT-----RDGLHINPRAAGLVGRDGP 345

  Fly   808 YLSTNPNRPFLV-------LHTESSRTRRVRRR------------------AVDCGGA-LNGQCC 846
            |    ..:||:|       :|..::|:...|||                  |.|...: |...|.
  Rat   346 Y----DKQPFMVAFFKVSEVHVRTTRSASSRRRQQSRNRSTQSQDVSRGSSASDYNSSELKTACK 406

  Fly   847 KESFYVSFKALGWDDWIIAPRGYFANYCRGDCT--------------------------GSFRTP 885
            |...||||:.|||.||||||:||.||||.|:|:                          |....|
  Rat   407 KHELYVSFQDLGWQDWIIAPKGYAANYCDGECSFPLNAHMNATNHAIVQTLVSALTWLVGPGLDP 471

  Fly   886 DTFQTF--HAHFIEEYRKMGLMNGMRPCCAPIKFSSMSLIYYGDD-GIIKRDLPKMVVDECGC 945
            .:|.|.  ||..:|:...|......:|||||.|.:::|::|:.|: .:|.:....|||..|||
  Rat   472 VSFLTVSSHASLLEQVHLMNPEYVPKPCCAPTKLNAISVLYFDDNSNVILKKYRNMVVRACGC 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Actbeta	NP_651942.2	TGFb_propeptide	370..>509	CDD:279078	22/134 (16%)
		TGF_beta	843..945	CDD:278448	45/130 (35%)
Bmp6	XP_038951315.1	TGFb_propeptide	58..355	CDD:395559	80/467 (17%)
		TGF_beta_BMP6	404..535	CDD:381666	47/131 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810