Protein Alignment Actbeta and Tgfb3

DIOPT Version :9

• Sequence 1: NP_651942.2
• Gene: Actbeta / 43826
• FlyBaseID: FBgn0024913
• Length: 946
• Species: Drosophila melanogaster
• Sequence 2: NP_033394.2
• Gene: Tgfb3 / 21809
• MGIID: 98727
• Length: 412
• Species: Mus musculus
• Alignment Length: 480
• Identity: 111/480 - (23%)
• Similarity: 176/480 - (36%)
• Gaps: 131/480 - (27%)

  Fly   512 IASMPIELKSHHNSSPKELKSGAVRK--VNGINGTQMNENALKKSTYPIDINH------SIDNKT 568
            :|::.:.|     |:...|..|.::|  |..|.|..:::..|.....|..:.|      ::.|.|
Mouse    17 LATISLSL-----STCTTLDFGHIKKKRVEAIRGQILSKLRLTSPPEPSVMTHVPYQVLALYNST 76

  Fly   569 HTGKNGEMSHNDYEYFNDYSVQTHDKNRYHEGRSSIGYQPAIHNIEYENQKGHHESFADDHENID 633
            .  :..|..|.:.|   :...|...::.|        |...||..:.......|...|...:.|.
Mouse    77 R--ELLEEMHGERE---EGCTQETSESEY--------YAKEIHKFDMIQGLAEHNELAVCPKGIT 128

  Fly   634 HEDFFGNTQEIITFAEEGTQ-YR-QYRILEFSAQNRRVPSQKLSIRSAQIHIRIDKPHSLWIEKA 696
            .:.|..|...:   .:.||. :| ::|:|       |||:.. |.|:.|   ||:....|
Mouse   129 SKVFRFNVSSV---EKNGTNLFRAEFRVL-------RVPNPS-SKRTEQ---RIELFQIL----- 174

  Fly   697 KSLPEKHLLNTKRKWGANKPHHRIKIWVFQLSTSINITEKGIDKAIIFRASFQVDPKNLGWQKFD 761
              .|::|:...:...|.|.|                  .:|..:                |..||
Mouse   175 --RPDEHIAKQRYIGGKNLP------------------TRGTAE----------------WLSFD 203

  Fly   762 LTDTIREW-YGHTSHEKLRLLIDCTGCGGRYSLHLFQTS-------------KLRG--NSSDY-- 808
            :|||:||| ....|:..|.:.|.|. |      |.||.:             |.:|  |..|:
Mouse   204 VTDTVREWLLRRESNLGLEISIHCP-C------HTFQPNGDILENVHEVMEIKFKGVDNEDDHGR 261

  Fly   809 -------LSTNPNRPFLVL-----HTESS--RTRRVRRRAVD---CGGALNGQCCKESFYVSFKA 856
                   ...:.:.|.|:|     |...|  :..:.::||:|   |...|...||....|:.|:.
Mouse   262 GDLGRLKKQKDHHNPHLILMMIPPHRLDSPGQGSQRKKRALDTNYCFRNLEENCCVRPLYIDFRQ 326

  Fly   857 -LGWDDWIIAPRGYFANYCRGDCTGSFRTPDTFQTFHAHFIEEYRKMGLMNGMRPCCAPIKFSSM 920
             ||| .|:..|:||:||:|.|.|. ..|:.|   |.|:..:..|..:.......|||.|.....:
Mouse   327 DLGW-KWVHEPKGYYANFCSGPCP-YLRSAD---TTHSTVLGLYNTLNPEASASPCCVPQDLEPL 386

  Fly   921 SLIYYGDDGIIKRDLPKMVVDECGC 945
            :::||.........|..|||..|.|
Mouse   387 TILYYVGRTPKVEQLSNMVVKSCKC 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Actbeta	NP_651942.2	TGFb_propeptide	370..>509	CDD:279078
		TGF_beta	843..945	CDD:278448	32/102 (31%)
Tgfb3	NP_033394.2	TGFb_propeptide	24..230	CDD:366248	60/285 (21%)
		TGF_beta_TGFB3	312..412	CDD:381656	33/105 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11848
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910