Protein Alignment Actbeta and Tgfb2

DIOPT Version :9

• Sequence 1: NP_651942.2
• Gene: Actbeta / 43826
• FlyBaseID: FBgn0024913
• Length: 946
• Species: Drosophila melanogaster
• Sequence 2: NP_001316036.1
• Gene: Tgfb2 / 21808
• MGIID: 98726
• Length: 442
• Species: Mus musculus
• Alignment Length: 502
• Identity: 110/502 - (21%)
• Similarity: 176/502 - (35%)
• Gaps: 168/502 - (33%)

  Fly   505 QLKINS------QIASMPIELKSHHNSSPKELKSGAVRKVNGINGTQMNENALKKSTYPIDINHS 563
            :||:.|      :...:|.|:.|.:||:...|:..|.|:.......:.:|....|..|.||:...
Mouse    47 KLKLTSPPEDYPEPDEVPPEVISIYNSTRDLLQEKASRRAAACERERSDEEYYAKEVYKIDMPSH 111

  Fly   564 IDNKT----HTGKNGEMSHNDYEYFNDYSVQTHDKNRYHEGRSSI--GYQPAIHNIEYENQKGHH 622
            :.::|    .|..:|.:                  ..:...:|.:  ||..||
Mouse   112 LPSETVCPVVTTPSGSL------------------GSFCSRQSQVLCGYLDAI------------ 146

  Fly   623 ESFADDHENIDHEDFFGNTQEIITFAEEGTQYRQY-RILEFSAQNRRVPSQKLSIRSAQIHI-RI 685
                                       ..|.||.| ||:.|........:..|.  .|:..: |:
Mouse   147 ---------------------------PPTFYRPYFRIVRFDVSTMEKNASNLV--KAEFRVFRL 182

  Fly   686 DKPHSLWIEKAKSLPEKHLLNTKRKWGANKPHHRIKIWVFQLSTSINI---TEKGID-KAIIFRA 746
            ..|.:...|:                         :|.::|:..|.::   |::.|| |.:..||
Mouse   183 QNPKARVAEQ-------------------------RIELYQILKSKDLTSPTQRYIDSKVVKTRA 222

  Fly   747 SFQVDPKNLGWQKFDLTDTIREWYGHTSHEKLRLLIDCTGCGGRYSLH----LFQTS-------- 799
            ..:       |..||:||.::||.    |.|.|.|      |.:.|||    .|..|
Mouse   223 EGE-------WLSFDVTDAVQEWL----HHKDRNL------GFKISLHCPCCTFVPSNNYIIPNK 270

  Fly   800 ------KLRG--NSSDYLS------------TNPNRPFLVL------HTESSRTRRVRRRAVD-- 836
                  :..|  .:|.|.|            |:...|.|:|      ..||.::.|.::||:|
Mouse   271 SEELEARFAGIDGTSTYASGDQKTIKSTRKKTSGKTPHLLLMLLPSYRLESQQSSRRKKRALDAA 335

  Fly   837 -CGGALNGQCCKESFYVSFKA-LGWDDWIIAPRGYFANYCRGDCTGSFRTPDTFQTFHAHFIEEY 899
             |...:...||....|:.||. ||| .||..|:||.||:|.|.|...:.:    .|.|...:..|
Mouse   336 YCFRNVQDNCCLRPLYIDFKRDLGW-KWIHEPKGYNANFCAGACPYLWSS----DTQHTKVLSLY 395

  Fly   900 RKMGLMNGMRPCCAPIKFSSMSLIYY-GDDGIIKRDLPKMVVDECGC 945
            ..:.......|||.......::::|| |:...|:: |..|:|..|.|
Mouse   396 NTINPEASASPCCVSQDLEPLTILYYIGNTPKIEQ-LSNMIVKSCKC 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Actbeta	NP_651942.2	TGFb_propeptide	370..>509	CDD:279078	2/3 (67%)
		TGF_beta	843..945	CDD:278448	32/103 (31%)
Tgfb2	NP_001316036.1	TGFb_propeptide	21..256	CDD:279078	60/309 (19%)
		TGF_beta	344..441	CDD:278448	32/102 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11848
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.870