Protein Alignment Actbeta and Nodal

DIOPT Version :9

• Sequence 1: NP_651942.2
• Gene: Actbeta / 43826
• FlyBaseID: FBgn0024913
• Length: 946
• Species: Drosophila melanogaster
• Sequence 2: NP_038639.2
• Gene: Nodal / 18119
• MGIID: 97359
• Length: 354
• Species: Mus musculus
• Alignment Length: 284
• Identity: 62/284 - (21%)
• Similarity: 107/284 - (37%)
• Gaps: 78/284 - (27%)

  Fly   669 VPSQKLSIRSAQIHIRIDKPHSLWIEKAKSLPEKHLLNTKRKWGANKPHHRIKIWVFQLSTSINI 733
            :||| ::..|....:.:.||.|.|::..::|.::.....::.|     |......|...||::
Mouse   141 IPSQ-VTFASGSTVLEVTKPLSKWLKDPRALEKQVSSRAEKCW-----HQPYTPPVPVASTNV-- 197

  Fly   734 TEKGIDKAIIFRASFQVDPKNLGWQKFDLTDTIREWYGHTSHEKLRLLIDCTGCGGRYSLHLFQT 798
                    ::..::...:.:.||.... |.:....|..    ::.:|.::..|.|.|...|..
Mouse   198 --------LMLYSNRPQEQRQLGGATL-LWEAESSWRA----QEGQLSVERGGWGRRQRRHHL-- 247

  Fly   799 SKLRGNSSDYLSTNPNRPFLVLHTESSRTRRVRRRAVDCGGALNGQCCKESFYVSFKALGWDDWI 863
                          |:|        |...|||:                  |.|.|..:||..||
Mouse   248 --------------PDR--------SQLCRRVK------------------FQVDFNLIGWGSWI 272

  Fly   864 IAPRGYFANYCRGDCTGSFRTPDTFQ-TFHAHFIEEYRKMGLMNGMRP------CCAPIKFSSMS 921
            |.|:.|.|..|.|:|...  ..:.|. |.||:.      ..|:...:|      ||||:|...:|
Mouse   273 IYPKQYNAYRCEGECPNP--VGEEFHPTNHAYI------QSLLKRYQPHRVPSTCCAPVKTKPLS 329

  Fly   922 LIYYGDDGIIKRDLPKMVVDECGC 945
            ::|..:..::......|:|:||||
Mouse   330 MLYVDNGRVLLEHHKDMIVEECGC 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Actbeta	NP_651942.2	TGFb_propeptide	370..>509	CDD:279078
		TGF_beta	843..945	CDD:278448	31/108 (29%)
Nodal	NP_038639.2	TGFb_propeptide	33..169	CDD:279078	8/28 (29%)
		TGFB	254..353	CDD:214556	34/124 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810