Protein Alignment Actbeta and tig-2

DIOPT Version :9

• Sequence 1: NP_651942.2
• Gene: Actbeta / 43826
• FlyBaseID: FBgn0024913
• Length: 946
• Species: Drosophila melanogaster
• Sequence 2: NP_504271.1
• Gene: tig-2 / 178864
• WormBaseID: WBGene00006570
• Length: 366
• Species: Caenorhabditis elegans
• Alignment Length: 440
• Identity: 101/440 - (22%)
• Similarity: 157/440 - (35%)
• Gaps: 156/440 - (35%)

  Fly   543 GTQMNENALKKSTYPIDINHSIDNKTHTGKNG-EMSHNDYEYFNDYSVQTHDKNRYHEGRSSIGY 606
            |.|:.|      .:.||||          .|| .:..|:|       |.|:.|..|.:
 Worm    45 GEQIRE------LFNIDIN----------PNGPAVKANNY-------VSTYMKRLYKQ------- 79

  Fly   607 QPAIHNIEYENQKGHHESFADDHENIDHEDFFGNTQEIITFAEEGTQYRQYRILEFSAQ--NRRV 669
               :.|  ||:.:.|:|...:...:.|                        ||:...||  :.|:
 Worm    80 ---LEN--YEHGENHNEEEVNAWLSAD------------------------RIVSHMAQEVSHRL 115

  Fly   670 PSQKLSIRSAQIHIRIDKPHSLWIEKAKSLPEKHLLNTKRKWGANKPHHRIKIWVFQLSTSINIT 734
            .....|||.|:.|:                |.|.        |.:....:::|.:
 Worm   116 DDGSYSIRFAKEHV----------------PAKE--------GQSIVRAQLRIHI---------- 146

  Fly   735 EKGIDKAIIFRASFQVDPKNLGWQKFDLTDTIREWYGHTSHEKLRLLIDCTGCGGRYSLHLFQTS 799
                 :.|:....|.::..||.      .||:.     .|.:...::.|.|....|:| || |.|
 Worm   147 -----QGIVSPVFFYIEDTNLP------GDTVL-----VSSDDPTVVTDVTTMVDRWS-HL-QLS 193

  Fly   800 KL-----RGNSSDYLSTNPNRPFLVLHTE-------SSRTRR-----------VRRRAVDCGGAL 841
            .|     |.:::|.|..   ..|||:..:       ..|:||           :|::......|.
 Worm   194 TLPIVTARASTNDELKI---EAFLVIALKDEDAGPPKKRSRRSASTTPISAPPMRQKVKRSESAY 255

  Fly   842 ------NGQCCKESFYVSFKALGWDDWIIAPRGYFANYCRGDCTGSFRTPDTFQTFHAHFIEEYR 900
                  |.:|.::..||.|..|||..|:|||.|:.|.||.|||:..| :.:...|.|| .::...
 Worm   256 FEKPNENERCQRKGLYVDFDILGWKQWVIAPEGFSAFYCSGDCSAPF-SKEMNATSHA-IVQSTL 318

  Fly   901 KMGLMNGMRPC-CAPIKFSSMSLIYYGDDGIIK----RDLPKMVVDECGC 945
            .....|...|. |||....|..:::...:..::    ||   ||||||||
 Worm   319 HRVRPNSTTPAKCAPSSLGSYKILFVDQNKQVQIKRYRD---MVVDECGC 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Actbeta	NP_651942.2	TGFb_propeptide	370..>509	CDD:279078
		TGF_beta	843..945	CDD:278448	36/106 (34%)
tig-2	NP_504271.1	TGF_beta_BMP5_like	264..366	CDD:381639	38/107 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810