Protein Alignment Actbeta and Mstn

DIOPT Version :9

• Sequence 1: NP_651942.2
• Gene: Actbeta / 43826
• FlyBaseID: FBgn0024913
• Length: 946
• Species: Drosophila melanogaster
• Sequence 2: NP_034964.1
• Gene: Mstn / 17700
• MGIID: 95691
• Length: 376
• Species: Mus musculus
• Alignment Length: 426
• Identity: 96/426 - (22%)
• Similarity: 159/426 - (37%)
• Gaps: 108/426 - (25%)

  Fly   557 PIDINHSIDNKTHTGKNGEMS------HNDYEYFNDYSVQTHDKNRYHEG--------RSSIGYQ 607
            |:|:|...:.:.:..|.|..:      :..|.......:|...|.|....        |..:...
Mouse    21 PVDLNEGSEREENVEKEGLCNACAWRQNTRYSRIEAIKIQILSKLRLETAPNISKDAIRQLLPRA 85

  Fly   608 PAIHNI--EYENQKGHHESFADDHE--NIDHEDFFGNTQEIITFAEEGTQYRQYR------ILEF 662
            |.:..:  :|:.|:       ||..  :::.:|:...|:.|||...|.....|..      ..:|
Mouse    86 PPLRELIDQYDVQR-------DDSSDGSLEDDDYHATTETIITMPTESDFLMQADGKPKCCFFKF 143

  Fly   663 SAQ---NRRVPSQKLSIRSAQIHIR-IDKPHSLWIEKAKSLPEKHLLNTKRKWGANKPHHRIKIW 723
            |::   |:.|.:|      ..|::| :..|.:::::..:.:  |.:.:..|..|       |:..
Mouse   144 SSKIQYNKVVKAQ------LWIYLRPVKTPTTVFVQILRLI--KPMKDGTRYTG-------IRSL 193

  Fly   724 VFQLSTSINITEKGIDKAIIFRASFQVDPKNLGWQKFDLTDTIREWYGHTSHEKLRLLIDCTGCG 788
            ...:|....|                       ||..|:...::.|.....          :..|
Mouse   194 KLDMSPGTGI-----------------------WQSIDVKTVLQNWLKQPE----------SNLG 225

  Fly   789 GRYSLHLFQTSKLRGNSSDYLSTNPN------RPFLVLHTESSRTRRVRRRAVDCG-GALNGQCC 846
                   .:...|..|..|...|.|.      .|||.:....:..|..|...:||. .:...:||
Mouse   226 -------IEIKALDENGHDLAVTFPGPGEDGLNPFLEVKVTDTPKRSRRDFGLDCDEHSTESRCC 283

  Fly   847 KESFYVSFKALGWDDWIIAPRGYFANYCRGDCTGSFRTPDTFQTF-HAHFIEEYRKMGLMNGMRP 910
            :....|.|:|.|| ||||||:.|.||||.|:|...|     .|.: |.|.:.:....|   ...|
Mouse   284 RYPLTVDFEAFGW-DWIIAPKRYKANYCSGECEFVF-----LQKYPHTHLVHQANPRG---SAGP 339

  Fly   911 CCAPIKFSSMSLIYY-GDDGIIKRDLPKMVVDECGC 945
            ||.|.|.|.::::|: |.:.||...:|.||||.|||
Mouse   340 CCTPTKMSPINMLYFNGKEQIIYGKIPAMVVDRCGC 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Actbeta	NP_651942.2	TGFb_propeptide	370..>509	CDD:279078
		TGF_beta	843..945	CDD:278448	41/103 (40%)
Mstn	NP_034964.1	TGFb_propeptide	37..250	CDD:366248	42/274 (15%)
		TGF_beta_GDF8	269..376	CDD:381658	45/116 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810