DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Actbeta and Inhbc

DIOPT Version :9

Sequence 1:	NP_651942.2	Gene:	Actbeta / 43826	FlyBaseID:	FBgn0024913	Length:	946	Species:	Drosophila melanogaster
Sequence 2:	NP_034695.1	Gene:	Inhbc / 16325	MGIID:	105932	Length:	352	Species:	Mus musculus

Alignment Length:	325	Identity:	84/325 - (25%)
Similarity:	129/325 - (39%)	Gaps:	69/325 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   628 DHENIDHEDFFGNTQEIITFAEEGTQYRQYRILEFSAQNRRVPSQKLSIRSAQIHIRIDKPHSLW 692
            :|:....|      .|||:||:..........|||....|.  :..:.:|..:....:..||:
Mouse    89 EHDQRQEE------YEIISFADTDLSSINQTRLEFHFSGRM--ASGMEVRQTRFMFFVQFPHN-- 143

  Fly   693 IEKAKSLPEKHLLNTKRKWGANKPHHRIKIWVFQ-LSTSINITEKGIDKAIIFRASFQVDPKNLG 756
                    ....:|             |::.|.: ..|::.:|           :.:.|.....|
Mouse   144 --------ATQTMN-------------IRVLVLRPYDTNLTLT-----------SQYVVQVNASG 176

  Fly   757 WQKFDLTDTIREWYGHTSHEKLRLLIDCTGCG-GRYSLHLFQTSKLRGNSSDYLSTNPNRPFLVL 820
            |.:..|....:                 ..|. |..:|.|...|:: .:||..|....:|||:..
Mouse   177 WYQLLLGPEAQ-----------------AACSQGHLTLELVPESQV-AHSSLILGWFSHRPFVAA 223

  Fly   821 HTESSRTRRVRRRAVDCGGALNGQCCKESFYVSFKALGWDDWIIAPRGYFANYCRGDC----TGS 881
            ........|||||.:||.|| :..||::.|:|.|:.:||:||||.|.||..|:|.|.|    .|.
Mouse   224 QVRVEGKHRVRRRGIDCQGA-SRMCCRQEFFVDFREIGWNDWIIQPEGYAMNFCTGQCPLHVAGM 287

  Fly   882 FRTPDTFQTFHAHFIEEYRKMGLMNGMRPCCAPIKFSSMSLIYYG-DDGIIKRDLPKMVVDECGC 945
            .....:|.|...:.::.....| ..|...||.|.....:||:||. |..|:|.|:|.|||:.|||
Mouse   288 PGISASFHTAVLNLLKANAAAG-TTGRGSCCVPTSRRPLSLLYYDRDSNIVKTDIPDMVVEACGC 351

Fly 946 945
Mouse 352 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Actbeta	NP_651942.2	TGFb_propeptide	370..>509	CDD:279078
Actbeta	NP_651942.2	TGF_beta	843..945	CDD:278448	39/106 (37%)
Inhbc	NP_034695.1	TGFB	247..352	CDD:214556	41/106 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	118	1.000	Domainoid score	I5825
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1385831at2759
OrthoFinder	1	1.000	-	-		FOG0000887
OrthoInspector	1	1.000	-	-		otm42993
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11848
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X477
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.920