Protein Alignment Actbeta and Lefty1

DIOPT Version :10

• Sequence 1: NP_651942.2
• Gene: Actbeta / 43826
• FlyBaseID: FBgn0024913
• Length: 946
• Species: Drosophila melanogaster
• Sequence 2: NP_034224.1
• Gene: Lefty1 / 13590
• MGIID: 107405
• Length: 368
• Species: Mus musculus
• Alignment Length: 337
• Identity: 73/337 - (21%)
• Similarity: 121/337 - (35%)
• Gaps: 87/337 - (25%)

  Fly   637 FFGNTQEI---ITFAEEGTQYRQYRILEFSAQNRRVPSQKLSIRSAQIHIRIDKPHSLWIEKAKS 698
            |..|.:|:   ...:|..|     .:|.|..:.|..|:.:|    .|..:|:.:         :.
Mouse    78 FSQNLREVAGRFLVSETST-----HLLVFGMEQRLPPNSEL----VQAVLRLFQ---------EP 124

  Fly   699 LPEKHLLNTKRKWGANKPHH---RIKI-WVFQLSTSINITEKGIDKAIIFRASFQVDPKNLGWQK 759
            :|...|...||.    .||.   |:.| |       :...:.|.::..:..:.. |.....||:.
Mouse   125 VPRTALRRQKRL----SPHSARARVTIEW-------LRFRDDGSNRTALIDSRL-VSIHESGWKA 177

  Fly   760 FDLTDTIREWYGHTSHEKLRLLIDCT------GCGGRYSLHLFQTSKLRGNSSDYLSTNPNRPFL 818
            ||:|:.:..|. ..|..:..||:..:      | .|.:|.|.......:|...   ......|.|
Mouse   178 FDVTEAVNFWQ-QLSRPRQPLLLQVSVQREHLG-PGTWSSHKLVRFAAQGTPD---GKGQGEPQL 237

  Fly   819 VLHTESSRTRRVRRRAVDCGGALN----------GQCCKESFYVSFKALGW-DDWIIAPRGYFAN 872
            .|||...:         |.|...|          .:||::..|:..:.:.| ::||:.|.|:...
Mouse   238 ELHTLDLK---------DYGAQGNCDPEAPVTEGTRCCRQEMYLDLQGMKWAENWILEPPGFLTY 293

  Fly   873 YCRGDCTGSFRTPDTFQTFHAHFIEEYRKMGLMNGMRPCCAPIKFSSMSLIYYGDDGIIKR---- 933
            .|.|.|   .:.|::. |....|:          |.|.|.|. :.:|:.:|....:|...|
Mouse   294 ECVGSC---LQLPESL-TSRWPFL----------GPRQCVAS-EMTSLPMIVSVKEGGRTRPQVV 343

  Fly   934 DLPKMVVDECGC 945
            .||.|.|..|.|
Mouse   344 SLPNMRVQTCSC 355

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Actbeta	NP_651942.2	TGF_beta_INHB	845..945	CDD:381630	27/104 (26%)
Lefty1	NP_034224.1	TGFb_propeptide	<43..203	CDD:480997	32/155 (21%)
		TGF_beta_LEFTY1_2	264..355	CDD:381636	27/105 (26%)