Protein Alignment Actbeta and mav

DIOPT Version :10

• Sequence 1: NP_651942.2
• Gene: Actbeta / 43826
• FlyBaseID: FBgn0024913
• Length: 946
• Species: Drosophila melanogaster
• Sequence 2: XP_061514506.1
• Gene: mav / 1280598
• VectorBaseID: AGAMI1_014275
• Length: 667
• Species: Anopheles gambiae
• Alignment Length: 813
• Identity: 176/813 - (21%)
• Similarity: 278/813 - (34%)
• Gaps: 226/813 - (27%)

  Fly   189 NHRRRRHRYTKRLHHLMQDNMSGFEQRLNFSDAKCQSLETNY-GTNYDLVQGGKLFSQS------ 246
            :|||          ||..|...    .:..:|..|::...:: .|.:..|..||..:.|
Mosquito    24 SHRR----------HLDPDERC----EMRSTDEPCRTTALSFRRTLHTPVARGKKHTYSYPHHHH 74

  Fly   247 ERSLLVSPLREIEAPWPAIHGSMRNCSKIKRNRANLIWLLIGLVWFEVKLINCNGISSSNYYASN 311
            ..:|...|.||:      :.|.:| |..:....:.|...|:.||..:.:.::.....:|...|:.
Mosquito    75 YTALTPPPHREV------VPGGVR-CRVVPSVVSFLSKFLLFLVICDSQTVSRAAFRTSVAAAAT 132

  Fly   312 LESHKGCTLCHESGKPNIYTDKDNPHTDYNIYNKYHSNNNFNKKTNQPHNNIAPSDEVRLESIKR 376
            :            |.|::|||        :|.:...|.::........  .:.||....:...|.
Mosquito   133 I------------GHPDVYTD--------SIISSGGSEDDGGGGGGDV--EVQPSSGAAINHTKL 175

  Fly   377 Q--ILTKLGLSHKPNVSHPLPKQFIWETIY-----RVDGGRMIPNNAFGSSGKNLDQKTIKLRAF 434
            |  :|..||||..|:|......|..:||.|     ||:..|.:       :|...|....:.:.|
Mosquito   176 QEIVLEGLGLSALPDVRLMDISQQEYETKYAEYLERVNRRRTL-------AGTTEDGWYEQRQLF 233

  Fly   435 ASPGS-HLFNGRGGRTDQRSERDPSHHKYRSPFDFTFNISKNNVYGKVLRNRSLERIDKKNSFLN 498
            ..||| |..|.|      :..|..|.|.........|:|.        :||.|..:       :.
Mosquito   234 RFPGSDHTLNHR------KLRRKRSLHNDYDLVYIRFDIP--------MRNASTGQ-------MT 277

  Fly   499 GWTENRQLKINSQIASMPIELKSHHNSSPKELKSGAVRKVNGINGTQMNENALKKSTYPIDINHS 563
            |:          |..|:..:.:..|....:|....||        .....|||..|: | ..:||
Mosquito   278 GF----------QSPSLYHDPRGQHGEEEEEEDDAAV--------VDNPANALDHSS-P-SSSHS 322

  Fly   564 IDNKTHTGKNGEMSHNDYEYFNDYSVQTHDKNRYHEGRSSIGYQPAIHNIEYENQKGHHESFADD 628
            |....|.....|:.....|...:.|:......|.:..||:        |...::|  ||..
Mosquito   323 IHRPGHRQSLSELPPISPENIEESSLNIMLTRRQNSARST--------NAHSKHQ--HHSQ---- 373

  Fly   629 HENIDHEDFFGNTQEIITFAEEGTQYRQYRILEFSAQNRRVPSQKLSIRSAQIH-------IRID 686
                                    |.:|...::.||.:......:|.....|.|       :|.
Mosquito   374 ------------------------QQQQAHQVQQSAPSPPASPAQLHQHQLQAHGHRRKGRVRF- 413

  Fly   687 KPHSLWIEKAKSLPEKHLLNTKRKWGANKPHH----RIKIWVFQLSTSIN---ITEKGIDKAIIF 744
            |.|......|..  ::|.|:         |||    .:.|.|:||.....   :|.|.:
Mosquito   414 KQHQQQHHHASQ--QQHQLH---------PHHPGRATVTIHVYQLVEPYERHFLTSKTV------ 461

  Fly   745 RASFQVDPKNLGWQKFDLTDTIREWYGHTSHEKLRLLIDCTGCGGRYSLHLFQTSKLRGNSSDYL 809
             |..::.|....|.:..|.:.:|.|. ..|.:.|.|.:.|.||..: .:|:..      :||.|.
Mosquito   462 -AVQEIPPNGSRWYQLPLEEAVRTWL-DGSRKNLGLELYCEGCHAQ-DVHIVH------DSSPYF 517

  Fly   810 STNPNRPF------LVLHTESSRTRRVRRRAVD---------CGGALNGQCCKESFYVSFKALGW 859
            .:....|.      ||...:.|:.:|.|.:..|         | .|.|.:||:....|.|:.:..
Mosquito   518 RSYDETPVLNVVGRLVQREKRSKLQRYRPQMRDYLSPPKTTAC-TAGNKRCCRHPLLVDFRDIEG 581

  Fly   860 DDWIIAPRGYFANYCRGDCTGSFRTPDTFQTFHAHFIEEYRKMGLMNGMRPCCAPIKFSSMSLIY 924
            .|:||.|:.:.|.:|||.|...| .|.|........:.|:.|..:   .:|||||   ||:..|
Mosquito   582 FDFIIQPKIFDAGFCRGRCPTKF-NPATHHALLQSLLHEHIKYDV---PKPCCAP---SSLDHI- 638

  Fly   925 YGDDGIIKRDLPK------------MVVDECGC 945
                .::..| ||            |.|.||.|
Mosquito   639 ----DVLHAD-PKNPQRLKVSTWHNMRVLECAC 666

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Actbeta	NP_651942.2	TGF_beta_INHB	845..945	CDD:381630	33/111 (30%)
mav	XP_061514506.1	None