Protein Alignment Actbeta and Bmp7

DIOPT Version :9

• Sequence 1: NP_651942.2
• Gene: Actbeta / 43826
• FlyBaseID: FBgn0024913
• Length: 946
• Species: Drosophila melanogaster
• Sequence 2: NP_031583.2
• Gene: Bmp7 / 12162
• MGIID: 103302
• Length: 430
• Species: Mus musculus
• Alignment Length: 559
• Identity: 124/559 - (22%)
• Similarity: 189/559 - (33%)
• Gaps: 198/559 - (35%)

  Fly   452 RSERDPSHHKY----------RSPF-DFTFNISKNNVYGKVL--RNRSLERIDKKNSFLNGWTEN 503
            ||.|..:.|.:          ||.. ||:.:   |.|:...:  |.||.||.:.:...|:
Mouse     4 RSLRAAAPHSFVALWAPLFLLRSALADFSLD---NEVHSSFIHRRLRSQERREMQREILS----- 60

  Fly   504 RQLKINSQIASMPIELKSH----HNSSPK---ELKSGAVRKVNGINGTQMNENALKKSTYPIDIN 561
                    |..:|...:.|    |||:|.   :|.:....:.:|.:|        :..:||....
Mouse    61 --------ILGLPHRPRPHLQGKHNSAPMFMLDLYNAMAVEESGPDG--------QGFSYPYKAV 109

  Fly   562 HSIDNKTHTGKNGEMSHNDYEYFND-------YSVQTHDKNRYHEGRSSIGYQPAIHNIEYENQK 619
            .|.......      |..|..:..|       .::..|||..:|                   .:
Mouse   110 FSTQGPPLA------SLQDSHFLTDADMVMSFVNLVEHDKEFFH-------------------PR 149

  Fly   620 GHHESFADDHENIDHEDFFGNTQEIITFAEEGTQYRQYR--ILEFSAQNRRVPSQKLSIRSAQIH 682
            .||..|..|...|..       .|.:|.||    :|.|:  |.|      |..::...|...|:
Mouse   150 YHHREFRFDLSKIPE-------GEAVTAAE----FRIYKDYIRE------RFDNETFQITVYQV- 196

  Fly   683 IRIDKPHSLWIEKAKSLPEKHLLNTKRKWGANKPHHRIKIWVFQLSTSINITEKGIDKAIIFRAS 747
                     ..|.:....:..||:::..|.:.:
Mouse   197 ---------LQEHSGRESDLFLLDSRTIWASEE-------------------------------- 220

  Fly   748 FQVDPKNLGWQKFDLTDTIREWYGHTSHEKLRLLIDCTGCGGRYSLHLFQTSKLRGNSSDYLSTN 812
                    ||..||:|.|...|..:..| .|.|.:......|: |::    .||.|....:...|
Mouse   221 --------GWLVFDITATSNHWVVNPRH-NLGLQLSVETLDGQ-SIN----PKLAGLIGRHGPQN 271

  Fly   813 PNRPFLV-------LHTESSRTRRVRRRAVDCGGALNGQ-------------------CCKESFY 851
             .:||:|       :|..|.|:...::|:.:.......|                   |.|...|
Mouse   272 -KQPFMVAFFKATEVHLRSIRSTGGKQRSQNRSKTPKNQEALRMASVAENSSSDQRQACKKHELY 335

  Fly   852 VSFKALGWDDWIIAPRGYFANYCRGDCT---GSFRTPDTFQTFHA------HFIEEYRKMGLMNG 907
            |||:.|||.||||||.||.|.||.|:|.   .|:..    .|.||      |||..      ...
Mouse   336 VSFRDLGWQDWIIAPEGYAAYYCEGECAFPLNSYMN----ATNHAIVQTLVHFINP------DTV 390

  Fly   908 MRPCCAPIKFSSMSLIYYGD-DGIIKRDLPKMVVDECGC 945
            .:|||||.:.:::|::|:.| ..:|.:....|||..|||
Mouse   391 PKPCCAPTQLNAISVLYFDDSSNVILKKYRNMVVRACGC 429

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Actbeta	NP_651942.2	TGFb_propeptide	370..>509	CDD:279078	16/69 (23%)
		TGF_beta	843..945	CDD:278448	43/130 (33%)
Bmp7	NP_031583.2	TGFb_propeptide	35..279	CDD:395559	67/363 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	290..310		2/19 (11%)
		TGF_beta_BMP7	324..430	CDD:381667	44/116 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810