Protein Alignment Actbeta and Bmp4

DIOPT Version :10

• Sequence 1: NP_651942.2
• Gene: Actbeta / 43826
• FlyBaseID: FBgn0024913
• Length: 946
• Species: Drosophila melanogaster
• Sequence 2: NP_031580.2
• Gene: Bmp4 / 12159
• MGIID: 88180
• Length: 408
• Species: Mus musculus
• Alignment Length: 404
• Identity: 93/404 - (23%)
• Similarity: 150/404 - (37%)
• Gaps: 117/404 - (28%)

  Fly   582 EYFND-YSVQTHDKNRYHEGRSSIGYQPAIHNIEYENQKGHHESFADDHENIDHEDFFGNTQEII 645
            :|..| |.:|:.::....:.:.:        .:||..:..   |.|:...:..||:...|    |
Mouse    81 DYMRDLYRLQSGEEEEEEQSQGT--------GLEYPERPA---SRANTVRSFHHEEHLEN----I 130

  Fly   646 TFAEEGTQYRQYRILEFSAQNRRVPSQKLSIRSAQIHIRIDKP---HSLWIEKAKSLPEK----H 703
            ....|.:.:|....|....:|..:.|.:|.:...|:....|..   |.:.|.:....|.:    |
Mouse   131 PGTSESSAFRFLFNLSSIPENEVISSAELRLFREQVDQGPDWEQGFHRINIYEVMKPPAEMVPGH 195

  Fly   704 LLNTKRKWGANKPHHRIKIWVFQLSTSINITEKGIDKAIIFRASFQVDPKNLGWQKFDLTDTIRE 768
            |:.  |.......||             |:|.                     |:.||::..:..
Mouse   196 LIT--RLLDTRLVHH-------------NVTR---------------------WETFDVSPAVLR 224

  Fly   769 W-------YGHTSHEKLRLLIDCTGCGGRYSLHLFQTSKLRG-----------NSSDYLSTNPNR 815
            |       ||        |.|:.|        ||.||...:|           .|.|:...   |
Mouse   225 WTREKQPNYG--------LAIEVT--------HLHQTRTHQGQHVRISRSLPQGSGDWAQL---R 270

  Fly   816 PFLVLHTESSR----TRRVRRRA----VDCGGALNGQCCKESFYVSFKALGWDDWIIAPRGYFAN 872
            |.||......|    |||..:|:    .......|..|.:.|.||.|..:||:|||:||.||.|.
Mouse   271 PLLVTFGHDGRGHTLTRRRAKRSPKHHPQRSRKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQAF 335

  Fly   873 YCRGDCTGSFRTPDTFQTFHAHFIEEYRKMGLMNGM-----RPCCAPIKFSSMSLIYYGD-DGII 931
            ||.|||  .|...|...:.:...::.     |:|.:     :.||.|.:.|::|::|..: |.::
Mouse   336 YCHGDC--PFPLADHLNSTNHAIVQT-----LVNSVNSSIPKACCVPTELSAISMLYLDEYDKVV 393

  Fly   932 KRDLPKMVVDECGC 945
            .::..:|||:.|||
Mouse   394 LKNYQEMVVEGCGC 407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Actbeta	NP_651942.2	TGF_beta_INHB	845..945	CDD:381630	35/105 (33%)
Bmp4	NP_031580.2	TGFb_propeptide	43..276	CDD:459906	50/264 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	91..111		2/27 (7%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	281..307		6/25 (24%)
		TGF_beta_BMP4_BMP2B	302..408	CDD:381661	38/113 (34%)