Protein Alignment Actbeta and Bmp2

DIOPT Version :10

• Sequence 1: NP_651942.2
• Gene: Actbeta / 43826
• FlyBaseID: FBgn0024913
• Length: 946
• Species: Drosophila melanogaster
• Sequence 2: NP_031579.2
• Gene: Bmp2 / 12156
• MGIID: 88177
• Length: 394
• Species: Mus musculus
• Alignment Length: 391
• Identity: 89/391 - (22%)
• Similarity: 150/391 - (38%)
• Gaps: 115/391 - (29%)

  Fly   593 DKNRYHEGRSSIGYQPAIHNIEYENQKG------HHESFADDHENIDHED---FFGNTQEIITFA 648
            |..|.|.|:.  |.....|.:|....:.      |||...::...:..:.   ||.|...
Mouse    80 DLYRRHSGQP--GAPAPDHRLERAASRANTVRSFHHEEAVEELPEMSGKTARRFFFNLSS----- 137

  Fly   649 EEGTQYRQYRILEFSAQNRRVPSQKLSIRSAQIHIRIDKPHSLWIEKAKSLPEKHLLNTKRKWGA 713
                                |||.:. :.||::.|..::     |::|              .|.
Mouse   138 --------------------VPSDEF-LTSAELQIFREQ-----IQEA--------------LGN 162

  Fly   714 NKPHHRIKIWVFQLSTSINI---TEKGIDKAIIFRASFQVDPKNLGWQKFDLTDTIREW--YGHT 773
            :...|||.|:......:.|:   ..:.:|..::.:.:.|       |:.||:|..:..|  .|||
Mouse   163 SSFQHRINIYEIIKPAAANLKFPVTRLLDTRLVNQNTSQ-------WESFDVTPAVMRWTTQGHT 220

  Fly   774 SH---EKLRLLIDCTGCGGRY-----SLHLFQTSKLRGNSSDYLSTNPNRPFLV----------L 820
            :|   .::..|.:..|...|:     |||           .|..|.:..||.||          |
Mouse   221 NHGFVVEVAHLEENPGVSKRHVRISRSLH-----------QDEHSWSQIRPLLVTFGHDGKGHPL 274

  Fly   821 HTESSRTRRVRRRAVDCGGALNGQCCKESFYVSFKALGWDDWIIAPRGYFANYCRGDCTGSFRTP 885
            |....|..:.::|.     .|...|.:...||.|..:||:|||:||.||.|.||.|:|  .|...
Mouse   275 HKREKRQAKHKQRK-----RLKSSCKRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGEC--PFPLA 332

  Fly   886 DTFQTFHAHFIEEYRKMGLMNGM-----RPCCAPIKFSSMSLIYYGD-DGIIKRDLPKMVVDECG 944
            |...:.:...::.     |:|.:     :.||.|.:.|::|::|..: :.::.::...|||:.||
Mouse   333 DHLNSTNHAIVQT-----LVNSVNSKIPKACCVPTELSAISMLYLDENEKVVLKNYQDMVVEGCG 392

  Fly   945 C 945
            |
Mouse   393 C 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Actbeta	NP_651942.2	TGF_beta_INHB	845..945	CDD:381630	32/105 (30%)
Bmp2	NP_031579.2	TGFb_propeptide	45..265	CDD:459906	50/249 (20%)
		TGF_beta_BMP2	292..394	CDD:381660	34/109 (31%)