DRSC/TRiP Functional Genomics Resources

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Protein Alignment Actbeta and Bmp10

DIOPT Version :9

Sequence 1:NP_651942.2 Gene:Actbeta / 43826 FlyBaseID:FBgn0024913 Length:946 Species:Drosophila melanogaster
Sequence 2:NP_033886.2 Gene:Bmp10 / 12154 MGIID:1338820 Length:421 Species:Mus musculus


Alignment Length:393 Identity:89/393 - (22%)
Similarity:141/393 - (35%) Gaps:139/393 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly   663 SAQNRRVPSQKLSIRSAQIHIRIDKP------HSLWIEKAKSLPEKHLL---------------N 706
            |.:|..:.:..||....|...|:|.|      ::.:.....|:|..:::               |
Mouse    57 SMKNEFLKTLNLSDIPVQDTGRVDPPEYMLELYNKFATDRTSMPSANIIRSFKNEDLFSQPVTFN 121

  Fly   707 TKRKW----GANKPHH--------RI----------------KIWVFQLSTSINITEKGIDKAII 743
            ..||:    ..:.|||        |:                ||.:|::..|.:.:|:  :::::
Mouse   122 GLRKYPLLFNVSIPHHEEVVMAELRLYTLVQRDRMMYDGVDRKITIFEVLESADGSEE--ERSML 184

  Fly   744 FRASFQVDPKNLGWQKFDLTDTIREWY--GHTSHEKLRLLIDC-------TGCGGRYSLHLFQTS 799
            ...|.::...|..|:.||:||..|.|.  |.::|: |.:.|:.       ||.|   .|.:    
Mouse   185 VLVSTEIYGTNSEWETFDVTDATRRWQKSGPSTHQ-LEIHIESRQNQAEDTGRG---QLEI---- 241

  Fly   800 KLRGNSSDYLSTNPNRPFLVLHTE----------------------------------------- 823
                   |..:.|.:.|.||:.::                                         
Mouse   242 -------DMSAQNKHDPLLVVFSDDQSNDKEQKEELNELITHEQDLDLDSDAFFSGPDEEALLQM 299

  Fly   824 -----SSRTRRVRRRAVDCGGALNGQCCKES-FYVSFKALGWDDWIIAPRGYFANYCRGDCT--- 879
                 ...:.|:||.|       .|..||:: .|:.||.:|||.|||||.||.|..|||.|.   
Mouse   300 RSNMIDDSSARIRRNA-------KGNYCKKTPLYIDFKEIGWDSWIIAPPGYEAYECRGVCNYPL 357

  Fly   880 GSFRTPDTFQTFHAHFIEEYRKMGLMNGMRPCCAPIKFSSMSLIYYGDDGII--KRDLPKMVVDE 942
            ....||    |.||...............:.||.|.|...:|::|. |.|::  |.....|.|.|
Mouse   358 AEHLTP----TKHAIIQALVHLKNSQKASKACCVPTKLDPISILYL-DKGVVTYKFKYEGMAVSE 417

  Fly   943 CGC 945
            |||
Mouse   418 CGC 420

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ActbetaNP_651942.2 TGFb_propeptide 370..>509 CDD:279078
TGF_beta 843..945 CDD:278448 39/107 (36%)
Bmp10NP_033886.2 TGFb_propeptide 55..256 CDD:279078 44/215 (20%)
TGF_beta 318..420 CDD:278448 38/106 (36%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3900
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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