Protein Alignment Actbeta and bmp5

DIOPT Version :10

• Sequence 1: NP_651942.2
• Gene: Actbeta / 43826
• FlyBaseID: FBgn0024913
• Length: 946
• Species: Drosophila melanogaster
• Sequence 2: XP_004914553.1
• Gene: bmp5 / 100494976
• XenbaseID: XB-GENE-479371
• Length: 449
• Species: Xenopus tropicalis
• Alignment Length: 543
• Identity: 116/543 - (21%)
• Similarity: 190/543 - (34%)
• Gaps: 173/543 - (31%)

  Fly   457 PSHHKYRSPFDFTFNISKNNVYGKVLRNRSLERIDKKNSFLNGWTEN-RQLKINSQIASMPIELK 520
            |.:|.:.|   |.:         :.|||...:.|.::...:.|.... |......|.:|.|:.:.
 Frog    25 PGNHVHSS---FIY---------RRLRNHERKEIQREILSILGLPHRPRPFSPGKQASSAPLFML 77

  Fly   521 SHHNSSPKELKSGAVRKVNGINGTQMNENALKKSTYPIDINHSIDNKTHTGKNGEM--------S 577
            ..:|:..||.....:...  ::|..:....|:|. ||: :.:....|....:|..:        |
 Frog    78 DLYNAMAKEDDHSMLGYT--LSGAMLESRGLRKG-YPV-VANGYSRKAQAYRNAPLTTQRPPLAS 138

  Fly   578 HNDYEYFNDYSVQTHDKNRYHEGRSSIGYQPAIHNIEYENQKGHHESFADDHENIDHEDFFGNTQ 642
            ..|..:.||..:.....|.....:            ::.:.:.|::.|..|...|.|       .
 Frog   139 LQDSNFLNDADMVMSFVNLVERDK------------DFSHNRRHYKEFRFDLTQIPH-------G 184

  Fly   643 EIITFAEEGTQYRQYRILEFSAQNRRVPSQKLSIRSAQIHIRIDKPHSLWIEKAKSLPEKHLLNT 707
            |.:|.||    :|.|:    ...|.|..::.|.|...|| |:         :.:....:..||:|
 Frog   185 EAVTAAE----FRIYK----DRSNNRFGNETLKISIYQI-IK---------DYSNRDADLFLLDT 231

  Fly   708 KRKWGANKPHHRIKIWVFQLSTSINITEKGIDKAIIFRASFQVDPKNLGWQKFDLTDTIREWYGH 772
            :|                                        |...::||..||:|.|...|..:
 Frog   232 QR----------------------------------------VQTYDVGWLVFDITVTSNHWVIN 256

  Fly   773 TSHEKLRLLIDCTGCGGRYSLHLFQTSKLRGNSSDYLSTNPNRPFLVLH-------------TES 824
            ..:.....|...|..|...|:   :::.|.|..    .....:||||..             |.:
 Frog   257 PQNNLGLQLCAETSDGRSVSV---KSAGLIGRH----GPQSKQPFLVAFFKASEVLLRSVRATNT 314

  Fly   825 SRTRRVRRRAV------------DCGGALNGQCCKE-SFYVSFKALGWDDWIIAPRGYFANYCRG 876
            .:.::.|.::.            |...:...|.||: ..||||:.|||:||||||.||.|.||.|
 Frog   315 KKKKQDRNKSTTSHDASRMPSIGDYNTSEQKQACKKHELYVSFRDLGWEDWIIAPEGYAAFYCDG 379

  Fly   877 DCTGSFRTPDTFQTFHAHFIEEYRKMGLMNGM------------------RPCCAPIKFSSMSLI 923
            :|  ||       ..:||          ||..                  :|||||.|.:::|::
 Frog   380 EC--SF-------PLNAH----------MNATNHAIVQTLVHLMFPDHVPKPCCAPTKLNAISVL 425

  Fly   924 YYGD-DGIIKRDLPKMVVDECGC 945
            |:.| ..:|.:....|||..|||
 Frog   426 YFDDSSNVILKKYRNMVVRSCGC 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Actbeta	NP_651942.2	TGF_beta_INHB	845..945	CDD:381630	42/119 (35%)
bmp5	XP_004914553.1	TGFb_propeptide	27..298	CDD:459906	67/370 (18%)
		TGF_beta_BMP5	337..449	CDD:381665	46/131 (35%)