Protein Alignment Actbeta and bmp8

DIOPT Version :10

• Sequence 1: NP_651942.2
• Gene: Actbeta / 43826
• FlyBaseID: FBgn0024913
• Length: 946
• Species: Drosophila melanogaster
• Sequence 2: XP_002941697.3
• Gene: bmp8 / 100494880
• XenbaseID: XB-GENE-485424
• Length: 425
• Species: Xenopus tropicalis
• Alignment Length: 375
• Identity: 85/375 - (22%)
• Similarity: 138/375 - (36%)
• Gaps: 127/375 - (33%)

  Fly   611 HNIEYENQKGHHESFADDHENIDHEDFFGNTQEIITFAEEGTQYRQYRILEFSAQNRRVPSQKLS 675
            |:.:...||.:.:.|..|...|.       |.|.:|.||    :|.:::..|.....|.
 Frog   137 HDRDIFQQKPYWKEFKFDMTQIP-------TGESVTVAE----FRLFKMRSFLRNLNRT------ 184

  Fly   676 IRSAQIHIRIDKPHSLWIEKAKSLPEKHLLNTKRKWGANKPHHRIKIWVFQLSTSINITEKGIDK 740
                 :||.:   ..:..|:....||..||:.:.....::
 Frog   185 -----LHISL---FEIKKERGHREPELTLLDHESTLAGDE------------------------- 216

  Fly   741 AIIFRASFQVDPKNLGWQKFDLTDTIREWYGHTSHE-KLRLLID----------CTGCGGR---- 790
                           ||..||:|.....|..::.:. .:||.::          ..|..||
 Frog   217 ---------------GWLVFDVTAASNHWLLNSKNNLGIRLYVETDQGQSIDPGIAGILGRRAPR 266

  Fly   791 ----YSLHLFQTSKLRGNSSDYLS------------TNPNR-PFLVLHTESSRTRRVRRRAVDCG 838
                :.:..|:.|:.:..|:..:.            .:||: |.::.|...:.:|:|
 Frog   267 SKQPFMVTFFRVSRNQIRSARAVKQLRKRQQKKHDLPHPNKLPGILDHLHVTDSRQV-------- 323

  Fly   839 GALNGQCCKESFYVSFKALGWDDWIIAPRGYFANYCRGDCTGSFRTPDTFQ-TFHAHFIEEYRKM 902
                  |.:...||||:.|||.||:|||:||.|.||.|:|  ||....... |.||..      .
 Frog   324 ------CKRHELYVSFRDLGWLDWVIAPQGYSAFYCEGEC--SFPLDSCMNATNHAIL------Q 374

  Fly   903 GLMNGMRP------CCAPIKFSSMSLIYY-GDDGIIKRDLPKMVVDECGC 945
            .|::.|:|      ||||.|.|:.|::|| .::.:|.:....|||..|||
 Frog   375 SLVHLMKPESVPKACCAPTKLSATSVLYYDSNNNVILKKHRNMVVKSCGC 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Actbeta	NP_651942.2	TGF_beta_INHB	845..945	CDD:381630	42/107 (39%)
bmp8	XP_002941697.3	TGFb_propeptide	35..275	CDD:459906	32/202 (16%)
		TGF_beta_BMP8	321..425	CDD:381668	46/126 (37%)