Protein Alignment Actbeta and inhbc.1

DIOPT Version :9

• Sequence 1: NP_651942.2
• Gene: Actbeta / 43826
• FlyBaseID: FBgn0024913
• Length: 946
• Species: Drosophila melanogaster
• Sequence 2: XP_002939470.1
• Gene: inhbc.1 / 100493888
• XenbaseID: XB-GENE-494358
• Length: 367
• Species: Xenopus tropicalis
• Alignment Length: 609
• Identity: 118/609 - (19%)
• Similarity: 193/609 - (31%)
• Gaps: 277/609 - (45%)

  Fly   348 SNNNFNKKTNQPHNNIAPSDEVRLESIKRQILTKLGLSHKPNVSHPLPKQFIWETIYRVDGGRMI 412
            |.....||:..|...: ...||.:|..|:|||.||.|..:||::||:|:..:...:.|:...:..
 Frog    24 STQGLTKKSQCPSCGV-QDKEVMMELAKQQILQKLHLKERPNITHPVPRGAVANALRRLHLNKPR 87

  Fly   413 PNNAFGSSGKNLDQKTIKLRAFASPGSHLFNGRGGRTDQRSERDPSHHKYRSPFDFTFNISKNNV 477
            ....|||.  |.|..|                ....|||:|
 Frog    88 MEGLFGSI--NWDSNT----------------ENTETDQQS------------------------ 110

  Fly   478 YGKVLRNRSLERIDKKNSFLNGWTENRQLKINSQIASMPIELKSHHNSSPKELKSGAVRKVNGIN 542
                                                                             
 Frog   111 ----------------------------------------------------------------- 110

  Fly   543 GTQMNENALKKSTYPIDINHSIDNKTHTGKNGEMSHNDYEYFNDYSVQTHDKNRYHEGRSSIGYQ 607
                         |.|                 :|..:.||.|:.|             :::.:|
 Frog   111 -------------YEI-----------------ISFAETEYSNEIS-------------TTLNFQ 132

  Fly   608 PAIHNIEYENQKGHHESFADDHENIDHEDFFGNTQEIITFAEEGTQYRQYRILEFSAQNRRVPSQ 672
                             |..|.|...|                        :|
 Frog   133 -----------------FTRDREQSTH------------------------VL------------ 144

  Fly   673 KLSIRSAQIHIRIDKPHSLWIEKAKSLPEKHLLNTKRKWGANKPHHRIKIWVFQLSTS--INITE 735
                   |.|        ||:          .....|   .::.:..|::::.|.:.|  |.|:|
 Frog   145 -------QAH--------LWL----------FFKANR---TSQQNETIRLYLVQEANSRRILISE 181

  Fly   736 KGIDKAIIFRASFQVDPKNLGWQKFDLTDTIREWYGHTSHEKLRLLIDCTGCGGRYSLHLFQTSK 800
            |            .::|:..|||.|.|..|::.:: ...::.|:|.::|.||         |.:.
 Frog   182 K------------LIEPRWTGWQTFSLKSTLQAFF-DGGNKSLQLELNCEGC---------QDAP 224

  Fly   801 LRGNSSDYLSTNPNRPFLV----LHTESSRTRRVRRRAVDCGGALNGQCCKESFYVSFKALGWDD 861
            :..|.:|     .::||||    :|.:|   ....:|:::|....| .||::.:||.||.:||:|
 Frog   225 VLINLND-----SHQPFLVAQAKVHEQS---HHATKRSLNCDQNSN-LCCRKDYYVDFKDIGWND 280

  Fly   862 WIIAPRGYFANYCRGDC----TGSFRTPDTFQTFHAHFIEEYRKMGLMNGMRPCCAPIKFSSMSL 922
            |||.|.||..|||.|.|    .|:   |....:||.......:...:.|.:..||.|.|...:|:
 Frog   281 WIIKPEGYQINYCMGLCPMHIAGA---PGMAASFHTTVFNLIKANNIQNAVNSCCVPTKRRPLSM 342

  Fly   923 IYYG-DDGIIKRDLPKMVVDECGC 945
            :|:. ::.|:|.|:..|:|:.|||
 Frog   343 LYFDRNNNILKTDIADMIVEACGC 366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Actbeta	NP_651942.2	TGFb_propeptide	370..>509	CDD:279078	24/138 (17%)
		TGF_beta	843..945	CDD:278448	37/106 (35%)
inhbc.1	XP_002939470.1	TGFb_propeptide	41..239	CDD:366248	69/455 (15%)
		TGF_beta_INHBC_E	264..367	CDD:381676	39/106 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	118	1.000	Domainoid score	I5766
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	190	1.000	Inparanoid score	I3759
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1385831at2759
OrthoFinder	1	1.000	-	-		FOG0000887
OrthoInspector	1	1.000	-	-		otm48117
Panther	1	1.100	-	-	O	PTHR11848
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X477
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.160