Protein Alignment Actbeta and tgfb2

DIOPT Version :10

• Sequence 1: NP_651942.2
• Gene: Actbeta / 43826
• FlyBaseID: FBgn0024913
• Length: 946
• Species: Drosophila melanogaster
• Sequence 2: XP_002936067.1
• Gene: tgfb2 / 100489680
• XenbaseID: XB-GENE-480560
• Length: 411
• Species: Xenopus tropicalis
• Alignment Length: 456
• Identity: 106/456 - (23%)
• Similarity: 179/456 - (39%)
• Gaps: 126/456 - (27%)

  Fly   536 RKVNGINGTQMNENALKKSTYPIDINHSIDNKTHTGKNGEMSHNDYEYFNDYSVQTHD--KNRYH 598
            :::..|.|..:::  ||.::.|.|.          .:.||:|.:....:|    .|.|  :.:.:
 Frog    35 KRIEAIRGQILSK--LKLNSPPEDY----------PEPGEVSQDVIAIYN----STRDLLQEKAN 83

  Fly   599 EGRSSIGYQPAIHNIEYENQKGHHESFADDHENIDHEDFFGNTQEIITFAEEGTQYRQYRILEFS 663
            |..:|.           |.::...|.:|.:...||...::  |.|.:......|.|  :||:.|.
 Frog    84 ERAASC-----------ERERSEDEYYAKEVYKIDMLPYY--TSENVIPPSYTTPY--FRIVRFD 133

  Fly   664 AQNRRVPSQKLSIRSAQIHIRIDKPHSLWIEKAKSLPEKHLLNTKRKWGANKPHHRIKIWVFQLS 728
            ..:    .:|.:....:...|:.:                |:|.|    |.....||::  :|:.
 Frog   134 VSS----MEKNASNLVKAEFRVFR----------------LMNPK----ARVSEQRIEL--YQIL 172

  Fly   729 TSINI---TEKGID-KAIIFRASFQVDPKNLGWQKFDLTDTIREWYGHTSHEKLRLLIDCTGCGG 789
            .|.::   |::.|| |.:..||..:       |..||:|:.|.||.    |.|.|.|      |.
 Frog   173 KSKDLASPTQRYIDSKVVKTRAEGE-------WLSFDVTEAINEWL----HHKDRNL------GF 220

  Fly   790 RYSLH------LFQTSKLRGNSSDYLST-------------NP----------NRPFLVL----- 820
            :.|||      :...:.:..|.|:.|.|             :|          ..|.|:|
 Frog   221 KISLHCPCCTFIPSNNYIIPNKSEELETRFAGIDDAYMYAGDPKTKSRKKHTGRTPHLLLMLLPS 285

  Fly   821 -HTESSRTRRVRRRAVD---CGGALNGQCCKESFYVSFKA-LGWDDWIIAPRGYFANYCRGDCTG 880
             ..||.::.|.::||:|   |...:...||....|:.||. ||| .||..|:||.||:|.|.|..
 Frog   286 YRLESQQSSRRKKRALDAAYCFRNVQDNCCLRPLYIDFKRDLGW-KWIHEPKGYNANFCAGACPY 349

  Fly   881 SFRTPDTFQTFHAHFIEEYRKMGLMNGMRPCCAPIKFSSMSLIYY-GDDGIIKRDLPKMVVDECG 944
            .:.:    .|.|:..:..|..:.......|||......|::::|| |:...|:: |..|:|..|.
 Frog   350 LWSS----DTQHSRVLSLYNTINPEASASPCCVSQDLDSLTILYYIGNKPKIEQ-LSNMIVKSCK 409

  Fly   945 C 945
            |
 Frog   410 C 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Actbeta	NP_651942.2	TGF_beta_INHB	845..945	CDD:381630	33/101 (33%)
tgfb2	XP_002936067.1	TGFb_propeptide	21..228	CDD:459906	57/266 (21%)
		TGF_beta_TGFB2	314..410	CDD:381655	33/101 (33%)