Protein Alignment Actbeta and gdf5

DIOPT Version :9

• Sequence 1: NP_651942.2
• Gene: Actbeta / 43826
• FlyBaseID: FBgn0024913
• Length: 946
• Species: Drosophila melanogaster
• Sequence 2: XP_002662587.1
• Gene: gdf5 / 100334210
• ZFINID: ZDB-GENE-990415-39
• Length: 474
• Species: Danio rerio
• Alignment Length: 362
• Identity: 89/362 - (24%)
• Similarity: 144/362 - (39%)
• Gaps: 95/362 - (26%)

  Fly   627 DDHENIDHEDFFGNTQEIITFAEEGTQ------YRQYRILEFSAQNRRVPSQKLSIRSAQIHIRI 685
            |.:.::.||....||  |.:|.:.|..      .||..:...|:.      :|..:..|::.|
Zfish   164 DVNTSVLHEAGMANT--ITSFVDRGQDERAPLLRRQRYVFNISSM------EKEGLLGAELRI-- 218

  Fly   686 DKPHSLWIEKAKSLPEKHLLNTKRKWGANKPHHRIKIWVFQLSTSINITEKGIDKAIIFRASFQV 750
                         |.:||:.:.|..:...       :.|.:|.|..:    |.:.|::.:|. ..
Zfish   219 -------------LRKKHMDSRKATFSEG-------MAVLRLFTCAS----GKNAAVLLQAR-PF 258

  Fly   751 DPKNLG-WQKFDLTDTIREWYGHTSHEKLRLLIDCTGCGGRYSLHL------------------F 796
            |..:.. |:.||:....:.:   .:..:|.|.:|....|....|.|                  |
Zfish   259 DSHSASYWEVFDIWKVFKNF---RNTPQLCLELDAVDHGRPLDLRLLGLSRAGRQTKEKAFFVVF 320

  Fly   797 QTSKLRG---NSSDYLSTNPNRP-FLVLHTESSRTRRVRRRAVDCGGA----LNGQCCKESFYVS 853
            ..:|.||   |.....|.:.|:. :..|.|:    ||:||..:..|..    ...:|.::..:|:
Zfish   321 GRTKKRGLFYNEIKARSGHDNKTVYEYLFTQ----RRMRRAPLPRGKKPIKNPKQRCNRKQLHVN 381

  Fly   854 FKALGWDDWIIAPRGYFANYCRGDCTGSFRT---PDTFQTFHAHFIEEYRKMGLMNGMRP----- 910
            ||.:|||||||||..|.|.:|.|.|....|:   |    |.|| .|:.     |||.|.|
Zfish   382 FKEMGWDDWIIAPLEYEAFHCDGVCDFPIRSHLEP----TNHA-IIQT-----LMNSMDPRSTPP 436

  Fly   911 -CCAPIKFSSMSLIYYGD-DGIIKRDLPKMVVDECGC 945
             ||.|.:.|.:|::|... :.::.:....|||:.|||
Zfish   437 TCCVPTRLSPISILYIDSANNVVYKQYEDMVVESCGC 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Actbeta	NP_651942.2	TGFb_propeptide	370..>509	CDD:279078
		TGF_beta	843..945	CDD:278448	39/111 (35%)
gdf5	XP_002662587.1	TGFb_propeptide	138..320	CDD:279078	34/193 (18%)
		TGF_beta	371..473	CDD:278448	39/111 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810