DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Actbeta and LOC100329520

DIOPT Version :9

Sequence 1:	NP_651942.2	Gene:	Actbeta / 43826	FlyBaseID:	FBgn0024913	Length:	946	Species:	Drosophila melanogaster
Sequence 2:	XP_002662616.2	Gene:	LOC100329520 / 100329520	-ID:	-	Length:	368	Species:	Danio rerio

Alignment Length:	307	Identity:	78/307 - (25%)
Similarity:	137/307 - (44%)	Gaps:	67/307 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   657 YRILEFSAQNRRVPSQ---KLSIRSAQIHIRIDKPHSLWIEKAKSLPEKHLLNTKRKWGANKPHH 718
            |.|:.|:..:..:|:.   .||.:..|     :|.||:.:.::
Zfish   110 YEIVSFADIDGDLPNSIDTSLSFQFLQ-----EKGHSVQVLQS---------------------- 147

  Fly   719 RIKIWVF-------QLSTSINITEKGIDKAIIFRASFQVDPKNLGWQKFDLTDTIREWYGHTSHE 776
              .:|::       ::|..|.::: ..::.::.:.|  ||....||..|.:|.|::.:. .....
Zfish   148 --SLWLYLRPSESSRISAEIYLSD-STNRTLVLQRS--VDAARGGWHTFPVTSTLQAFL-DGGQR 206

  Fly   777 KLRLLIDCTGCGGRYSLHLFQTSKLRGNSSDYLSTNPNRPFLVLHT---ESSRTRRVRRRAVDCG 838
            :|||.:.|...|    .:|.:......:|        ::||||...   |......:.:|::.||
Zfish   207 RLRLEVQCQDAG----RNLCKKEPTEDSS--------HQPFLVAQVRLREDPSKHALSKRSLRCG 259

  Fly   839 GALNGQCCKESFYVSFKALGWDDWIIAPRGYFANYCRGDC----TGSFRTPDTFQTFHAHFIEEY 899
            ..:. .|||:.||:.|:.:.|.||||||.||..|||.|.|    :||   |....:|||....:.
Zfish   260 DDVT-VCCKKDFYIKFRDIQWQDWIIAPEGYHMNYCMGQCPQHLSGS---PGIASSFHASVFSQL 320

  Fly   900 RKMGLMNGMRPCCAPIKFSSMSLIYYGDD-GIIKRDLPKMVVDECGC 945
            :..|:...:..||.||:...:|::|:... .|:|.|:|.|:|:.|||
Zfish   321 KANGINTAVSSCCVPIQRRPLSMVYFNSQHTIVKTDVPDMIVESCGC 367

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Actbeta	NP_651942.2	TGFb_propeptide	370..>509	CDD:279078
Actbeta	NP_651942.2	TGF_beta	843..945	CDD:278448	40/106 (38%)
LOC100329520	XP_002662616.2	TGFb_propeptide	54..238	CDD:279078	31/172 (18%)
LOC100329520	XP_002662616.2	TGF_beta	265..367	CDD:278448	40/104 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	121	1.000	Domainoid score	I5640
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	190	1.000	Inparanoid score	I3867
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1385831at2759
OrthoFinder	1	1.000	-	-		FOG0000887
OrthoInspector	1	1.000	-	-		otm24667
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11848
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X477
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	9.070