Protein Alignment sv and pax8

DIOPT Version :9

• Sequence 1: NP_524633.3
• Gene: sv / 43825
• FlyBaseID: FBgn0005561
• Length: 844
• Species: Drosophila melanogaster
• Sequence 2: XP_012814730.1
• Gene: pax8 / 780226
• XenbaseID: XB-GENE-483693
• Length: 467
• Species: Xenopus tropicalis
• Alignment Length: 663
• Identity: 209/663 - (31%)
• Similarity: 269/663 - (40%)
• Gaps: 265/663 - (39%)

  Fly   175 GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHNGVRPCDISRQLRVSHGCVSKIL-SRYYETGSFK 238
            ||||:|||||.||||||||:|||||||:|||.|||||||||||||||||||||| ||||||||.:
 Frog    26 GHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGSRYYETGSIR 90

  Fly   239 AGVIGGSKPKVATPPVVDAIANYKRENPTMFAWEIRDRLLAEAICSQDNVPSVSSINRIVRNKAA 303
            .|||||||||||||.||:.|.:|||:||||||||||||||||.:|..|.||||||||||:|.
 Frog    91 PGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRIIRT--- 152

  Fly   304 EKAKHVHHHQQHHVSQSLGGGHIATESVDSSTGTIGEPQPPTSNSSANSVNTNVSASASVHASIP 368
             |.:.:.:.......:||..|.....|     ..:..|:.|.|:|
 Frog   153 -KVQQLFNLPMESCVKSLSPGQTLIPS-----SAVTPPESPHSDS-------------------- 191

  Fly   369 TSGTDSVQVSVGHINANSNETTHINSTAEQRTTGYSINGILGI-QHGHHSHNNNNNSSVNNNNNT 432
                                   :.||       |||:|:||| |.|
 Frog   192 -----------------------LGST-------YSISGLLGITQPG------------------ 208

  Fly   433 ESSCKRKRIEAHDENHDTNIHSDNDDGKRQRMSTYSGDQLYTNIWSGKWCIKDDHKLLAELGNLT 497
             :..|||..::..|:...:|.|....|       .|..||.|..:.        |..|..|
 Frog   209 -ADGKRKLDDSDQESCRLSIDSQGSMG-------ISRKQLRTEAYG--------HHPLDAL---- 253

  Fly   498 ASTGNC-------PATYYEASNGFSTTPISGSGATASGNDTSMLYDSITTISQTQSSIYT-PAIG 554
                .|       |.:|                             |.:|.|:|:.::|| |.:.
 Frog   254 ----ECHFQRQHFPESY-----------------------------SSSTHSKTEQALYTLPLLN 285

  Fly   555 PSI--GTGSLTPLVP-----ISMHE-----MKLSANSIQEQTVPPFYTALAFDGNYTSMTSLENC 607
            .::  |..|||....     :|.|:     .:|||.:|:::         |.|.:..|.|....|
 Frog   286 NAMDDGKSSLTSTNTTIGRNLSTHQGYSALSELSAFTIKQE---------ASDSSSASSTPSSLC 341

  Fly   608 SSLVGQEHIVMPESSDSNTLCPISTRIVPDITETNSTRVKEPLTNSDGCSEDNNKEPEKSNSSQS 672
            |          |...|   |.|||:                      |||
 Frog   342 S----------PTFLD---LQPISS----------------------GCS--------------- 356

  Fly   673 SDHIASPHLHHIGEEQLRGNRRSNLNASTHPSSL----IPLQPSG----GSSLLNINPSENRSDV 729
                 :|                :.:|.:||:|:    .....||    ||:|....|
 Frog   357 -----AP----------------SFSAFSHPASVYGQFTSHMASGRDVVGSTLPGYPP------- 393

  Fly   730 ELNLSNNVGLYSTPTVLPSFNHYSAGCSSVVPGSDYAYNPAYTQYGGAYGSYGYG---TGSGLIN 791
              ::.:..|.|::          ||....|..|.||:.| ||:.  |||.:||..   ..|.|:.
 Frog   394 --HIPSGQGNYAS----------SAIAGMVAAGGDYSGN-AYSH--GAYAAYGESWRFPSSSLLG 443

  Fly   792 SSYYYESGQTQSP 804
            |.|||.|....:|
 Frog   444 SPYYYSSATRTAP 456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sv	NP_524633.3	PAX	175..299	CDD:128645	104/124 (84%)
pax8	XP_012814730.1	PAX	26..151	CDD:128645	104/124 (84%)
		Pax2_C	355..465	CDD:372091	37/160 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	231	1.000	Domainoid score	I2385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	268	1.000	Inparanoid score	I2957
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D268681at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm48797
Panther	1	1.100	-	-	O	PTHR45636
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X862
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	9.070