Protein Alignment sv and Pax7

DIOPT Version :10

• Sequence 1: NP_524633.3
• Gene: sv / 43825
• FlyBaseID: FBgn0005561
• Length: 844
• Species: Drosophila melanogaster
• Sequence 2: XP_006239325.1
• Gene: Pax7 / 500574
• RGDID: 1564360
• Length: 505
• Species: Rattus norvegicus
• Alignment Length: 643
• Identity: 165/643 - (25%)
• Similarity: 237/643 - (36%)
• Gaps: 252/643 - (39%)

  Fly   175 GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHNGVRPCDISRQLRVSHGCVSKILSRYYETGSFKA 239
            |.|.||||||||:||||||:.:|.:|||:||:|:|||.||||||||||||||||.||.||||.:.
  Rat    34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRP 98

  Fly   240 GVIGGSKPK-VATPPVVDAIANYKRENPTMFAWEIRDRLLAEAICSQDNVPS--VSSINRIVRNK 301
            |.||||||: ||||.|...|..||||||.||:||||||||.:..|.:..|||  ||||:|::|.|
  Rat    99 GAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSISRVLRIK 163

  Fly   302 AAEKAKHVHHHQQHHVSQSLGGGHIATESVDSSTGTIGEPQPPTSNSSANSVNTNVSASASVHAS 366
            ..:|.                         |...|...|..
  Rat   164 FGKKE-------------------------DDEEGDKKEED------------------------ 179

  Fly   367 IPTSGTDSVQVSVGHINANSNETTHINSTAEQRTTGYSINGILGIQHGHHSHNNNNNSSVNNNNN 431
                                          .::...:||:||||          :..:.::..::
  Rat   180 ------------------------------GEKKAKHSIDGILG----------DKGNRLDEGSD 204

  Fly   432 TESS----CKRKR---------------IEAHDENHDTNIHSDNDDGKRQRMSTYSGDQLYTNIW 477
            .||.    .|||:               .:|.:..|..:|::..:..:|.:::     :....:|
  Rat   205 VESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLT-----EARVQVW 264

  Fly   478 ----SGKWCIKDDHKLLAELGNLTASTGNCPATYYEASNGFSTTPISGSGATASGNDTSMLYDS- 537
                ..:|..:.....||...:|.  .|..|.|      |..|.|            ...|.||
  Rat   265 FSNRRARWRKQAGANQLAAFNHLL--PGGFPPT------GMPTLP------------PYQLPDSA 309

  Fly   538 --ITTISQT-QSSIYTPAIGPSIGTGSLTPLVPISMHEMKLSANSIQEQTVPPFYTALAFDGNYT 599
              .||:||. .|:::.|           .||.|.:||:..|:|            .|.|.|.
  Rat   310 YPTTTVSQDGGSTVHRP-----------QPLPPSTMHQGGLAA------------AAAAADS--- 348

  Fly   600 SMTSLENCSSLVGQEH-------IVMPESSDSNTLCPISTRIVPDITETNSTRVKEPLTNSDGCS 657
                    ||..|..|       ..|...:.||.:.|:|..:.|.:
  Rat   349 --------SSAYGARHSFSSYSDSFMNPGAPSNHMNPVSNGLSPQV------------------- 386

  Fly   658 EDNNKEPEKSNSSQSSDHIASPHLHHIGEEQLRGNRRSNLNASTHPSSLIPLQPSGGSSLLNINP 722
                                                   ::..::||: :|.||....|:..::.
  Rat   387 ---------------------------------------MSILSNPSA-VPPQPQADFSISPLHG 411

  Fly   723 S-ENRSDVELNLSNNVGLYSTPTVLPSFNHYSAGCSSVVPGSDYAYNPA----YTQYG 775
            . ::.|.:..:.|...........||:...|   |......:.|:.:|.    |:|||
  Rat   412 GLDSASSISASCSQRADSIKPGDSLPTSQSY---CPPTYSTTGYSVDPVAGYQYSQYG 466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sv	NP_524633.3	PAX	175..299	CDD:128645	86/126 (68%)
Pax7	XP_006239325.1	PAX	34..161	CDD:128645	86/126 (68%)
		Homeodomain	218..274	CDD:459649	6/60 (10%)
		Pax7	<354..385	CDD:403540	6/30 (20%)