Protein Alignment sv and toy

DIOPT Version :10

• Sequence 1: NP_524633.3
• Gene: sv / 43825
• FlyBaseID: FBgn0005561
• Length: 844
• Species: Drosophila melanogaster
• Sequence 2: NP_001368990.1
• Gene: toy / 43833
• FlyBaseID: FBgn0019650
• Length: 655
• Species: Drosophila melanogaster
• Alignment Length: 712
• Identity: 207/712 - (29%)
• Similarity: 306/712 - (42%)
• Gaps: 200/712 - (28%)

  Fly   165 HSSQG-----SISGDGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHNGVRPCDISRQLRVSHGCV 224
            |||.|     ..|..||.|:||||||:||||||||..||:||||||:|.|||||||.|:||:|||
  Fly    14 HSSVGQSTLFGCSTAGHSGINQLGGVYVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCV 78

  Fly   225 SKILSRYYETGSFKAGVIGGSKPKVATPPVVDAIANYKRENPTMFAWEIRDRLLAEAICSQDNVP 289
            ||||.|||||||.|...||||||:|||.|||..||:||||.|::||||||||||:|.:|:.||:|
  Fly    79 SKILGRYYETGSIKPRAIGGSKPRVATTPVVQKIADYKRECPSIFAWEIRDRLLSEQVCNSDNIP 143

  Fly   290 SVSSINRIVRNKAAEKAKHVHHHQQHHVSQSLGGGHIATESVDSSTGTIGEPQPPTSNSSANSVN 354
            |||||||::||.|::|.:.. ..|...|.:.|       ...:..||  |....|::.::|
  Fly   144 SVSSINRVLRNLASQKEQQA-QQQNESVYEKL-------RMFNGQTG--GWAWYPSNTTTA---- 194

  Fly   355 TNVSASASVHASIPTSGTDSVQVSVGHINANSNETTHINSTAEQRTTGYSINGILGIQHGHHSHN 419
                     |.::|.:.  ||..|..:::..::     ....::|...:|:.    :.|.:...:
  Fly   195 ---------HLTLPPAA--SVVTSPANLSGQAD-----RDDVQKRELQFSVE----VSHTNSHDS 239

  Fly   420 NNNNSSVNNNNNTESSCKRKRIEAHDENHDTNIHSDNDDG--------------KRQRMSTYSG- 469
            .::.:|.:|::..|.|..|.|::...:.:.|:..::..|.              .|:|::...|
  Fly   240 TSDGNSEHNSSGDEDSQMRLRLKRKLQRNRTSFSNEQIDSLEKEFERTHYPDVFARERLADKIGL 304

  Fly   470 DQLYTNIW----SGKWCIKDDHKLLAELGNLTASTGNCPATYYEASNGFSTTPISGSGATASGND 530
            .:....:|    ..||  :.:.|:..:  ..:|.|                  :.|||.|::.|:
  Fly   305 PEARIQVWFSNRRAKW--RREEKMRTQ--RRSADT------------------VDGSGRTSTANN 347

  Fly   531 TS--MLYDSITTISQTQSSIYTPAIGPSIGTGSLTPLVPISMHEMKLSANSIQEQTVPPFYTALA 593
            .|  ....|:.|.:.:...|...||..:..|.|            .|.:||:.|.:..|  |.|.
  Fly   348 PSGTTASSSVATSNNSTPGIVNSAINVAERTSS------------ALVSNSLPEASNGP--TVLG 398

  Fly   594 FDGNYTSMTSLENCSSLVGQEHIVMPESSDSNTLCPISTRIVPDITETNSTRVKEPLTNSDGCSE 658
            .:.|.|.                   .||:|..|.|.:.|:              ||.:......
  Fly   399 GEANTTH-------------------TSSESPPLQPAAPRL--------------PLNSGFNTMY 430

  Fly   659 DNNKEP-----EKSNSSQSS-------DHIASPHLHH----IGEEQLRGNRRSNLNASTHPSSLI 707
            .:..:|     |..|||..|       ...|.|::.|    :|...:..:.|   |.:.:||:..
  Fly   431 SSIPQPIATMAENYNSSLGSMTPSCLQQRDAYPYMFHDPLSLGSPYVSAHHR---NTACNPSAAH 492

  Fly   708 PLQPSGGSSLLNINPSENRSDVELNLSNNVGLYSTPTVLPSFNH--YSAGCSSVVPGSDYAYNPA 770
            ...|..                        |:|:..:.:||.|.  .|||.|..|..|
  Fly   493 QQPPQH------------------------GVYTNSSPMPSSNTGVISAGVSVPVQIS------- 526

  Fly   771 YTQYGGAYGSYGYGTGSGLINSSYY---YESGQTQSPLTHDLRSPLVATRANSLASAASPGS 829
             ||           ..|.|..|:|:   ..|....|||.|..:    ||.|..:|:.|:..|
  Fly   527 -TQ-----------NVSDLTGSNYWPRLQXSSIFGSPLDHLSK----ATAAAIIAAQAAEKS 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sv	NP_524633.3	PAX	175..299	CDD:128645	92/123 (75%)
toy	NP_001368990.1	PAX	29..153	CDD:128645	92/123 (75%)
		COG5576	<253..368	CDD:227863	23/136 (17%)
		Homeodomain	267..322	CDD:459649	8/56 (14%)