Protein Alignment sv and Vsx2

DIOPT Version :10

• Sequence 1: NP_524633.3
• Gene: sv / 43825
• FlyBaseID: FBgn0005561
• Length: 844
• Species: Drosophila melanogaster
• Sequence 2: NP_001284897.1
• Gene: Vsx2 / 31469
• FlyBaseID: FBgn0263512
• Length: 645
• Species: Drosophila melanogaster
• Alignment Length: 738
• Identity: 125/738 - (16%)
• Similarity: 220/738 - (29%)
• Gaps: 305/738 - (41%)

  Fly     6 IQTSTHHIHGLGTHELQHRILHPHILHSTQEETLNTSTGQLEHDSQH------------LQQHHL 58
            :..:.||.|   .|:.||   |||                  |...|            ..|||.
  Fly   132 LAAAVHHHH---QHQHQH---HPH------------------HHPHHPHGAVGGPPPPPPMQHHH 172

  Fly    59 THHQQQDVSPTLH-----NLQNTRTGDSLSTTINTNQNQHGHQHLSGSNMYTSSQMEDKSKANKY 118
            .||...   |.||     .|::...|.......:......|.:.|:|..:..:|:.:.|.:.:..
  Fly   173 PHHPHH---PLLHAQGFPQLKSFAAGAGTCLPGSLAPKDFGMESLNGFGVGPNSKKKKKKRRHSR 234

  Fly   119 DEYSSRTLSNISDANTTPSANNFITQSQGIEWITAMNDIQNGAEDSHSSQGSISGDGHGGVNQLG 183
            ..::|..|..:.:|                            .:::|
  Fly   235 TIFTSYQLEKLEEA----------------------------FKEAH------------------ 253

  Fly   184 GVFVNGRPLPDVVRQRIV----ELAHNGVRPCDISRQL------RVSHGCVSKILSRYYETGSFK 238
                    .|||..:.::    ||..:.::....:|:.      :|..|  |.|::.|
  Fly   254 --------YPDVYAREMLSLKTELPEDRIQVWFQNRRAKWRKTEKVWGG--STIMAEY------- 301

  Fly   239 AGVIGGSKPKVATPPVVDAIANYKRENPTMFAWEI--------RDRLLAEAICSQDNVPSVSSIN 295
             |:.|.....  :.|:.|.|....::|..:..|.:        |..:.|::....|:  .||...
  Fly   302 -GLYGAMVRH--SLPLPDTILKSAKDNDAVAPWLLGMEQKCMHRKSIEAQSALKDDS--GVSDHE 361

  Fly   296 RIVRNKAAEKAKHVHHHQQHHVSQSLGGGHIATESVDSSTGTIGEPQPPTSNSSANSVNTNVSAS 360
            ....:|:|. ::.:...:.|.:|.|....::.:.:..|...:.....||||.|       ..:.:
  Fly   362 DSAGSKSAH-SEDLSRSRCHALSSSTESLNVVSPAPSSCPTSASTSAPPTSTS-------GYAGA 418

  Fly   361 ASVHASIPTSGTDSVQVSVGHINANSNETTHINSTAEQRTTGYSINGILGIQHGHHSHNNNNNSS 425
            ||..|:.||          |....||:.:.||.               ||
  Fly   419 ASSAATTPT----------GASTTNSSSSPHIE---------------LG--------------- 443

  Fly   426 VNNNNNTESSCKRKRIEAHDENHDTNIHSDNDDGKRQRMSTYSGDQLYTNIWSGKWCIKDDHKLL 490
                  :.|..:::.::...:             ::|:.|.|
  Fly   444 ------SPSPQQQQHLQLQQQ-------------QQQQASLY----------------------- 466

  Fly   491 AELGNLTASTGNCPATYY---EASNGFSTTPISGSGATASGNDTSMLYDSITTIS---------- 542
              ||.....||..|.:|:   :|:|.      :|:||.||..|..|:.::....:
  Fly   467 --LGAGAVVTGCAPPSYHPLLDAANA------AGAGAAASSKDFHMIMNTAVAAAAAAAQQQHQQ 523

  Fly   543 QTQSSIYTPAIGPSIGTGSLTPLVPISMHEMKLSANSIQEQTVPPFYTALAFDGNYTSMTSLENC 607
            |.|......|..|             .:|...|:|..::..  |.     ||..|..:      |
  Fly   524 QQQQQQQATATAP-------------GLHAHNLAAALMEHD--PD-----AFRNNSIA------C 562

  Fly   608 SSLVGQEH------------------------------IVMPESSDSNTLCPISTRIVPDITETN 642
            .....|||                              :.:.|..::|:..||     |....|.
  Fly   563 LRAKAQEHQARLLNNGGLFLQVRRFAQGQAQIQDPSDMLKLSEEHNNNSPIPI-----PPAHSTV 622

  Fly   643 STR--VKEPLTNSDGCSEDNNKE 663
            :|:  ||..|| ::|.|..|.:|
  Fly   623 NTQVNVKMELT-ANGGSMKNYEE 644

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sv	NP_524633.3	PAX	175..299	CDD:128645	23/141 (16%)
Vsx2	NP_001284897.1	Homeodomain	230..287	CDD:459649	10/110 (9%)
		OAR	556..572	CDD:461067	5/21 (24%)