Protein Alignment sv and pax7a

DIOPT Version :10

• Sequence 1: NP_524633.3
• Gene: sv / 43825
• FlyBaseID: FBgn0005561
• Length: 844
• Species: Drosophila melanogaster
• Sequence 2: NP_571400.1
• Gene: pax7a / 30587
• ZFINID: ZDB-GENE-990415-201
• Length: 507
• Species: Danio rerio
• Alignment Length: 633
• Identity: 175/633 - (27%)
• Similarity: 248/633 - (39%)
• Gaps: 230/633 - (36%)

  Fly   175 GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHNGVRPCDISRQLRVSHGCVSKILSRYYETGSFKA 239
            |.|.||||||||:||||||:.:|.:|||:||:|:|||.||||||||||||||||.||.||||.:.
Zfish    34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRP 98

  Fly   240 GVIGGSKPK-VATPPVVDAIANYKRENPTMFAWEIRDRLLAEAICSQDNVP-----SVSSINRIV 298
            |.||||||: ||||.|...|..||||||.||:|||||:||.:.:|.:..||     |||||:|::
Zfish    99 GAIGGSKPRQVATPDVEKRIEEYKRENPGMFSWEIRDKLLKDGVCDRGTVPSGEASSVSSISRVL 163

  Fly   299 RNKAAEKAKHVHHHQQHHVSQSLGGGHIATESVDSSTGTIGEPQPPTSNSSANSVNTNVSASASV 363
            |.:..:|
Zfish   164 RARFGKK---------------------------------------------------------- 170

  Fly   364 HASIPTSGTDSVQVSVGHINANSNETTHINSTAEQRTTGYSINGILGIQHGHHSHNNNNNSSVNN 428
                                .:.:|....:...|::|. :||:|||    |...:..:..|.|.:
Zfish   171 --------------------DDDDECDKKDEDGEKKTK-HSIDGIL----GDKGNRTDEGSDVES 210

  Fly   429 NNNTESSCKRKRI-------------EAHDENHDTNIHSDNDDGKRQRMSTYSGDQLYTNIW--- 477
            ..:.....|::|.             :|.:..|..:|::..:..:|.:::     :....:|
Zfish   211 EPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLT-----EARVQVWFSN 270

  Fly   478 -SGKWCIKDDHKLLAELGNLTASTGNCPATYYEASNGFSTTPISGSGATASGNDTSMLYDSI--- 538
             ..:|..:.....||...:|.  .|..|.|      |..|.|            |..|.:|.
Zfish   271 RRARWRKQAGANQLAAFNHLL--PGGFPPT------GMPTLP------------TYQLPESTYPS 315

  Fly   539 TTISQTQSS-IYTPAIGPSIGTGSLTPLVPISMHEMKLSANSIQEQTVPPFYTALAFDGNYTSMT 602
            ||:||..|| ::.|           .||.|.|||:..|||:|                |:...::
Zfish   316 TTLSQDGSSTLHRP-----------QPLPPSSMHQGGLSADS----------------GSAYGLS 353

  Fly   603 SLENCSSLVGQEHIVMPESSDSNTLCPISTRIVPDITETNSTRVKEPLTNSDGCSEDNNKEPEKS 667
            |  |..:........|..::.||.:.|:|..:.|        :|...|:|           |...
Zfish   354 S--NRHTFSSYSETFMSPTASSNHMNPVSNGLSP--------QVMSILSN-----------PSAV 397

  Fly   668 NSSQSSDHIASPHLHHIGEEQLRGNRRSNLNASTHPSSLIPLQPSGGSSLLNINPSENRSDVELN 732
            .|....|...|| ||            ..|.||.      |:..|          ...|||...:
Zfish   398 PSQPQHDFSISP-LH------------GGLEASN------PISAS----------CSQRSDPIKS 433

  Fly   733 LSNNVGLYSTPTVLPSFNHYSAGCSSVVPGSDYAYNPA-----YTQYG 775
            :.:   |.||.:..|.  .|||        :.|:.:|.     |:|||
Zfish   434 VDS---LASTQSYCPP--TYSA--------TSYSVDPVTAGYQYSQYG 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sv	NP_524633.3	PAX	175..299	CDD:128645	85/129 (66%)
pax7a	NP_571400.1	PAX	34..166	CDD:238076	86/131 (66%)
		Homeodomain	221..277	CDD:459649	7/60 (12%)
		Pax7	343..386	CDD:403540	12/68 (18%)