Protein Alignment sv and pax2a

DIOPT Version :10

• Sequence 1: NP_524633.3
• Gene: sv / 43825
• FlyBaseID: FBgn0005561
• Length: 844
• Species: Drosophila melanogaster
• Sequence 2: XP_021336170.1
• Gene: pax2a / 30425
• ZFINID: ZDB-GENE-990415-8
• Length: 504
• Species: Danio rerio
• Alignment Length: 715
• Identity: 221/715 - (30%)
• Similarity: 282/715 - (39%)
• Gaps: 291/715 - (40%)

  Fly   171 ISGDGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHNGVRPCDISRQLRVSHGCVSKILS------ 229
            :|..|||||||||||||||||||||||||||||||.||||||||||||||||||||||.
Zfish    15 LSHIGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGSYQKDL 79

  Fly   230 -RYYETGSFKAGVIGGSKPKVATPPVVDAIANYKRENPTMFAWEIRDRLLAEAICSQDNVPSVSS 293
             |||||||.|.|||||||||||||.||:.||.|||:||||||||||||||||.:|..|.||||||
Zfish    80 IRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSS 144

  Fly   294 INRIVRNKAAEKAKHVHHHQQHHVSQSLGGGHIATESVDSSTGTIGEPQPPTSNSSANSVNTNVS 358
            ||||:|.|.         .|..|               .||.|| |.|.....::..:..:|..:
Zfish   145 INRIIRTKV---------QQPFH---------------PSSDGT-GTPLSTAGHTIGDLESTPYT 184

  Fly   359 ASASVHASIPTSGTDSVQVSVGHINANSNETTHINSTAEQRTTGYSINGILGIQHGHHSHNNNNN 423
            .:.|...|:|::.:..|                 :|.:......|||||||||.
Zfish   185 LTYSCALSVPSTASPPV-----------------SSASNDPVGSYSINGILGIP----------- 221

  Fly   424 SSVNNNNNTESSCKRKRIEAHDENHDTNIHSDNDDGKRQRMSTYSGDQLYTNIWSGKWCIKDDHK 488
                 .:|.|   ||||                ||                .:|||      :|.
Zfish   222 -----RSNGE---KRKR----------------DD----------------VLWSG------NHL 240

  Fly   489 LLAELGNLTASTGNCPATYYEASNGFSTTPISGSGATASGNDTSMLYDSITTISQTQSSIYTPAI 553
            ...::|             |..|:|      ||..:.:.|:..| |...:...:.||..:  .|:
Zfish   241 DGRKIG-------------YYGSDG------SGPNSDSQGSVES-LRKHLRADAFTQQQL--EAL 283

  Fly   554 GPSIGTGSLTPLVPISMHEMKLSANSIQ--------EQTVPPFYTALAFDGNYTSMTSLENCSSL 610
            .......|...:.|.|.|.....||...        ::..|...|:::.|           ..|.
Zfish   284 DRVFERPSYPDVFPTSEHIKPEQANEYSLPALNPGLDEVKPSLSTSVSSD-----------LGSS 337

  Fly   611 VGQEHIVMPESSDSNTLCPISTRIVPDITETNSTRVKEPLTNSDGCSEDNNKEPEKSNSSQSSDH 675
            |.|.:.|:.| |.|:::|                 ||:              ||
Zfish   338 VSQSYPVVTE-SHSSSMC-----------------VKQ--------------EP----------- 359

  Fly   676 IASPHLHHIGEEQLRGNRRSNLNASTHPSSLIPLQP-----SGGSSLLNINPSENRSDVELNLSN 735
                                      |.:||.|..|     ||.:.||.:.||     |.::.|.
Zfish   360 --------------------------HEASLAPFTPSSLAVSGLAELLPLQPS-----VSVDAST 393

  Fly   736 N-VGLYS--------------------TPTVLPSF----------NHYSAGCSSVVPGSDYAYN- 768
            . .|.|:                    ..|.||.:          ::.::..:.:|||||::.|
Zfish   394 PCYGAYAHHAPSYCQYTSQHIIAGREMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSDFSGNP 458

  Fly   769 ---PAYTQYGGAYGSYGYGTGSGLINSSYYYESGQTQSPLTHDLRSPLVATRANSLASAASPGSG 830
               |.||.|..|:..    :...|::|.|||                          ||||.|||
Zfish   459 YSHPQYTTYNEAWRF----SNPALLSSPYYY--------------------------SAASRGSG 493

  Fly   831  830
            Zfish   494  493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sv	NP_524633.3	PAX	175..299	CDD:128645	109/130 (84%)
pax2a	XP_021336170.1	PAX	19..150	CDD:128645	109/130 (84%)
		Zinc_peptidase_like	<257..377	CDD:472712	33/202 (16%)
		Pax2_C	391..503	CDD:463563	29/133 (22%)