DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sv and mixl1

DIOPT Version :9

Sequence 1:	NP_524633.3	Gene:	sv / 43825	FlyBaseID:	FBgn0005561	Length:	844	Species:	Drosophila melanogaster
Sequence 2:	NP_571015.3	Gene:	mixl1 / 30115	ZFINID:	ZDB-GENE-000208-20	Length:	327	Species:	Danio rerio

Alignment Length:	310	Identity:	61/310 - (19%)
Similarity:	98/310 - (31%)	Gaps:	111/310 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   370 SGTDSVQVSVGHINANSNETTHINSTAEQRTTGYSI--NGILGIQHGHHSHNNNNNSSVNNNNNT 432
            :|....::.|...|..:.....:..:...:|:|..:  |.:|  .|...:|  .|:|.:.|...|
Zfish    95 TGLPESRIQVWFQNRRAKSRRQVGISIPNKTSGNILTPNNLL--MHQFTTH--QNHSGLENLQRT 155

  Fly   433 ESSCKRKRIEAHDENHDTNIHSDNDDGKRQRMSTYSGDQLY--TNIWSGKWC---------IKDD 486
            .:.       ..|..|...|:|     ..:::||..|| :|  |.|    .|         ||.|
Zfish   156 STF-------TADSFHQQLINS-----SEEKISTIKGD-IYDPTTI----PCMFSRTQENPIKTD 203

  Fly   487 HKLLAELGNLTASTGNCPATYYEASNGFSTTPISGSGATASGNDTSMLYDSITTISQ--TQSSIY 549
            |..:.           .|.:|.:      ..|......|.|.|...      :|:.|  .:...:
Zfish   204 HLSVV-----------VPRSYTQ------QYPKEHEQFTHSANHAK------STMKQFLVEYDNF 245

  Fly   550 TP--AIGPSIGTGSLTPLVPISMHEMKLSANSIQEQTVPPFYTALAFDGNYTSMTSLENCSSLVG 612
            .|  .|||                |||:        .:||                      |..
Zfish   246 PPNKTIGP----------------EMKV--------VIPP----------------------LPS 264

  Fly   613 QEHIVMPESSDSNTLCPI---STRIVPDITETNS-TRVKEPLTNSDGCSE 658
            |.:.:|..||..:..|.:   |.:..|::..|.| .|..|.:..||..|:
Zfish   265 QSNFMMSSSSPKHIACSVQNMSVQTQPELFATFSPIRASEAVEFSDSDSD 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sv	NP_524633.3	PAX	175..299	CDD:128645
mixl1	NP_571015.3	Homeobox	61..114	CDD:278475	3/18 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.900